Rinsho Hyoka(Clinical Evaluation)
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1973 | 1 | 1 | 27 | A Double-Blind Controlled Study on the Clinical Efficacy of Four Antidepressant Drugs−clomipramine, dimethacrine, nortriptyline, and protriptyline | Hitoshi Itoh | Yukio Kawakita | Yoshio Kudo | Yorio Satoh | et al. |
1973 | 1 | 1 | 52 | The effect of a new analgesic Seda Kyorin on cancerous pain compared with sulpyrin a controlled, double-blind cross study. | Yukimitsu Tai | Kouichi Kaneda | Toshihiko Tanaka | Kouichi Yatomi | et al. |
1973 | 1 | 1 | 71 | A controlled clinical trial of Methylcobalamin in the treatment of peripheral neuropathy−A comparison of 1500μg/day with 120μg/day oral administraation− | Kyotaro Abe | Mitsuo Iida | Tetsuo Inokuchi | Tsugio Okada | et al. |
1973 | 1 | 1 | 77 | Double Blind Study of Cinnarizine on Cerebrovascular Diseases | Yorio Satoh | Masanao Kurihara | Hitoshi Itoh | Yoshiaki Tazaki | et al. |
1973 | 1 | 1 | 96 | The Validity of Psychoneurosis Rating Scale for Symptom on the differential diagnostic use between normal and psychoneurosis | Seiichi Ichimaru | Hitoshi Itoh | Yukio Kawakita | Masanao Kurihara | et al. |
1973 | 1 | 1 | 113 | Comparison of three kinds of antiparkinsonian agents(Piroheptine=FK-1190, Trihexyphenidyl and Promethazine) in drug-induced extrapyramidal symptoms using double-blind technique | Sadanori Miura | Masashi Takesada | Nobuo Tanaka | et al. | |
1973 | 1 | 2,3 | 139 | Clinical Effect of Placenta Extract "PLP injection" on Gastric Ulcer −Comparison of PLP injection with Basic Aluminium Sucrose Sulfate by Double Blind Test Method− | Yasuhiko Odori | Fumio Mizuno | et al. | ||
1973 | 1 | 2,3 | 149 | Further Analysis of the Double-Blind Controlled Study on the Clinical Efficacy of Four Antidepressant Drugs−Imipramine, Trimipramine, Safrazine, Amitriptyline | Yorio Satoh | Seiichi Ichimaru | et al. | ||
1973 | 1 | 2,3 | 167 | A Survey and study on Extra-Normal validity of The CPRG Depression Rating Scale For Patient's Use | Masazumi Shinozaki | Ikuo Hasue | Hideto Mori | Kenpei Miyakawa | Yorio Satoh |
1973 | 1 | 2,3 | 181 | Double blind controlled study of mesoridazine and thioridazine on schizophrenic inpatients | Hideto Mori | Motoo Arai | et al. | ||
1973 | 1 | 2,3 | 213 | Double blind cross-over comparison of clinical efficacy among two cholagogous,3-chloropyridazinyl-6-mercaptoacetic acid diethylamide and oxaphenamide,and placebo on cholestatic diseases. | Akima Miyoshi | Yorio Satoh | |||
1973 | 1 | 2,3 | 219 | Double Blind Study of the Effects of Lysozyme Eye Drops on Oculopathy | Masato Hayakawa | Sachio Uchida | Kazuko Kameyama | Yasuo Niwa | |
1973 | 1 | 2,3 | 233 | A case report of thallium intoxication | Muneo Shimizu | Yasunori Oana | Takayuki Saruhara | Kakumi Kurohane | Yorio Satoh |
1973 | 1 | 2,3 | 239 | Two fatal cases in the course of double-blind study of two antidepressants,doxepin and imipramine | Sousuke Tobisawa | Kenji Tsuburaya | Koichiro Shirahashi | ||
1973 | 1 | 2,3 | 243 | The double-blind controlled study on the mucolytic effects of S-carboxymethylcysteine orally administered. | Genichi Tanaka | Shigeru Nagaoka | Mitsuaki Endo | Shinichi Tanimoto | |
1974 | 2 | 1 | 9 | The effect of Butoxybenzyl Hyoscyamine Bromide as a pretreatment agent on X-ray examination using double-blind technique | Takeshi Tomioka | Kunihiko Sakaguchi | Katsunori Saigenji | Kunio Nanka | |
1974 | 2 | 1 | 23 | Comparison of Efficacy of Lithium Carbonate and Chlorpromazine in Mania by Double-Blind Controlled Study | Kozo Itoh | Hitoshi Itoh | Masanao Kurihara | et al. | |
1974 | 2 | 1 | 47 | A Double Blind Cross-Over Study of Clomipramine, Amitriptyline and Placebo on enuretic patients | Ryuichi Oogoshi | Yukio Fukuyama | et al. | ||
1974 | 2 | 1 | 69 | Clinical Trials of Timepidium Bromide(SA-504)for the Treatment of Abdominal Pain in Gastrointestinal Disease(A Double-Blind Controlled Trial) | Kiyoko Imamura | Makoto Osada | et al. | ||
1974 | 2 | 1 | 105 | A Double Blind Controlled Study of FX-501 on the Clinical Efficacy for Abdominal Pains | Masayoshi Namiki | ||||
1974 | 2 | 1 | 121 | Paradoxical behavioral reaction with skin rash after receiving amitriptyline | Toshihiro Takaishi | ||||
1974 | 2 | 2 | 139 | PhaseT Study of 2-Phenyl-5-benzothiazoleacetic acid(K-308) T.A Single-dose study | Hideo Miyashita | Naokata Shimizu | et al. | ||
1974 | 2 | 2 | 157 | PhaseT Study of 2-Phenyl-5-benzothiazoleacetic acid(K-308) U.A multiple-dose study | Hideo Miyashita | Naokata Shimizu | et al. | ||
1974 | 2 | 2 | 169 | Comparison of Clinical Efficacy of Clozapine and Haloperidol in Schizophrenia using Double-Blind Techniquie | Sadanori Miura | Iwao Tashiro | et al. | ||
1974 | 2 | 2 | 207 | Therapeutic Effect of Timepidium Bromide(Sesden) on Abdominal Pain due to Gastrointestinal Diseases−Evaluation by Double Blind Test− | Taneomi Okuhara | Goro Kajiyama | et al. | ||
1974 | 2 | 2 | 229 | A clinical evaluation of Glycopyrronium bromide on the peptic ulcers in the method of double blind controlled trial | Taneomi Okuhara | Takashi Kai | et al. | ||
1974 | 2 | 2 | 247 | A Comparative Double-Blind Clinical Study of Fluocinonide with Betamethasone Valerate | |||||
1974 | 2 | 2 | 259 | A Double-Blind Comparison of the Therapeutic and Side Effects of the Syrup and Tablet forms of Antihistaminic Drug, Tavegyl in Urticaria | |||||
1974 | 2 | 2 | 271 | A Doube-Blind Controlled Study on the Clinical Efficacy of Topical Betamethasone 17,21-Dipropionate | |||||
1974 | 2 | 3 | 335 | A Double-Blind Controlled Study of Ca Hopantonate and Pyrithioxine in Conformity to a Rating List for the Evaluation of the Abnormal Behaviors in Children(T) | |||||
1974 | 2 | 3 | 365 | A Double-Blind Controlled Study of Ca Hopantenate and Pyrithioxine in Conformity to a Rating List for the Evaluation of the Abnormal Behaviors in Children(U) | |||||
1974 | 2 | 3 | 375 | A Double-Blind Controlled Study of Ca Hopantenate and Placebo in Conformity to a Rating List for the Evaluation of the Abnormal Behaviors in Children(V) | |||||
1974 | 2 | 3 | 385 | Double-blind cross-over study of the clinical efficacy of nimetazepam (S-1530) on insomnia in comparison of nitrazepam and placebo | Hitoshi Itoh | Tetsuya Hirose | et al. | ||
1974 | 2 | 3 | 409 | A Double-blind Comparison of PJ-929 with Carpipramine in Chronic Schizophrenia | Haruhiko Naito | Sumio Sato | et al. | ||
1974 | 2 | 3 | 429 | Effect of Citicoline(CDP-choline) on Cerebrovascular Diseases −A controlled clinical trial with a double-blind method− | Eiichi Ohtomo | Shinzaburo Koshijima | et al. | ||
1974 | 2 | 3 | 441 | A Double-Blind Controlled Trial on The Antivertigious Effect of CDP-Choline(NICHOLINE) in The Cases with Posttraumatic Dizziness | Y.Koike | M.Nagaba | et al. | ||
1975 | 3 | 1 | 19 | Clinical efficacy of so-called brain metabolism activating agents in treatment of cerebrovascular disorders−A double-blind controlled study on the clinical efficacy of meclofenoxate and pyrithioxine in cerebrovascular disorders− | |||||
1975 | 3 | 1 | 47 | A double-blind controlled study of a β-glucuronidase inhibitor, aceglatone, on dysfunctional uterine bleeding | Tsutomu Ishiwara | Ryo Yonekura | et al. | ||
1975 | 3 | 1 | 55 | Comparison of Efficacy of M-2H,Bromvalerylurea,Nitrasepam and Placebo for Insomniac Patients by Double-Blind Controlled Study | Ryuichi Kodama | Yoshiyuki Shibata | et al. | ||
1975 | 3 | 1 | 71 | Double-blind cross-over study of the effect of LS-121 on cerebrovascular disease | Y.Tsunashima | Y.Kobayashi | et al. | ||
1975 | 3 | 2 | 135 | PhaseU Study on New Anti-inflammatory Agent 2-Phenyl-5-Benzothiazoleacetic Acid(K-308)−Clinical use in the treatment of acute inflammatory disease of the respiratory tract− | Syoji Kudo | ||||
1975 | 3 | 2 | 149 | A Multi-Clinic Double-Blind Controlled Study on The Clinical Efficacy of Dimetacrine and Amitriptyline in Depression | Takuro Noguchi | Michio Okada | et al. | ||
1975 | 3 | 2 | 177 | Comparison of Clinical Effect on Neurosis of Lorazepam, Diazepam and Placebo using Double Blind Technique | Nobuo Ohtsuka | Sadanori Miura | et al. | ||
1975 | 3 | 3 | 297 | A Multi-institutional Double Blind Controlled Study of Dilazep (AS-05) on the Effect for Ischemic Heart Diseases | Mitsuo Hisamatsu | Takashi Fujita | et al. | ||
1975 | 3 | 3 | 319 | The Efficacy of L-DOPA on Alopecia in the Method of Double Blind Controlled Study | |||||
1975 | 3 | 3 | 329 | Evaluation of Bencyclane on Cerebral Vascular Diseases−Multi-center, double-blind study in comparison with cinnarizine and placebo− | Takeshi Honma | Shigeo Hasegawa | et al. | ||
1975 | 3 | 3 | 357 | Clinico-Pharmacological Study of Ifenprodil (FX-505)−T.Study of urinary excretion and clinical safety in man | Hiroshi Kawai | ||||
1975 | 3 | 3 | 377 | Clinico-Pharmacological Study of Ifenprodil (FX-505)−U.Effects of Ifenprodil on the cerebral hemodynamics in young adults and CVD patients− | Jiro Kaneko | Junzo Shiraishi | Hisashi Inaoka | ||
1975 | 3 | 3 | 387 | Double Blind Study of FX-505 (Ifenprodil) on Cerebrovascular Disease−Phase U Study− | Ryuichi Kodama | Yasushi Maki | et al. | ||
1976 | 4 | 1 | 21 | Clinical Evaluation of Proglumide on Peptic Ulcers by Double Blind Test Method | Kazunori Ida | Yoshihiro Kori | et al. | ||
1976 | 4 | 1 | 41 | A Double-Blind Comparative Study on the Clinical Efficacy of Topical Betamethasone 17-benzoate | |||||
1976 | 4 | 1 | 61 | The Evaluation of Clinical Effects of Lucidril on the Psychiatric Symptoms of Patients with Cerebro-vascular Disorder | Toru Kawajiri | Osamu Yamada | Nobuo Yauchi | Masahiro Ota | |
1976 | 4 | 1 | 79 | A Double-Blind Controlled Study on the Clinical Efficacy of New Antihypertensive Agent; Bietaserpine | |||||
1976 | 4 | 1 | 101 | Comparison of Clinical Effects of Penfluridol, a Long-Acting Oral Neuroleptic, and Perphenazine in Schizophrenia using Double-Blind Technique | Sadanori Miura | Gohei Yagi | et al. | ||
1976 | 4 | 1 | 131 | A Clinical Effect of Ko 1366 on Angina Pectoris−A Comparative Double-Blind Clinical Study with Propranolol− | Kizuku Kuramoto | Akira Sakuma | et al. | ||
1976 | 4 | 2 | 189 | A Double Blind Controlled Study on the Clinical Efficacy of Antiinflammatory Analgesic, 31252-S on Orthopedics−The comparison of 31252-S, benzydamine hydrochloride and placebo− | Nobuyasu Ichikawa | ||||
1976 | 4 | 2 | 213 | Clinical Efficacy of Pentoxifylline (BL 191) and Pyrithioxine Hydrochloride (PTX) in Treatment of Cerebrovascular Disorders−A double blind controlled study− | Goro Araki | Katsuya Itahara | et al. | ||
1976 | 4 | 2 | 231 | Effect of Cyanocobalamine Ophthalmic Solution on Experimental Asthenopia | |||||
1976 | 4 | 2 | 241 | Effect of Cyanocobalamine Ophthalmic Solution on Experimental Asthenopia−By using Accommodometer, Osaka Univ.− | |||||
1976 | 4 | 2 | 247 | A Multicenter Double Blind Study of Carbenoxolone Sodium for Patients with Gastric Ulcer in Japan, Evaluated by Group Comparison with Nonparametric Analysis | Makoto Ishikawa | Takeo Wada | et al. | ||
1976 | 4 | 2 | 271 | A Side Effect Check System Model by Pattern Analysis | Haruko Shikimori | Kazuko Sei | Toshiharu Fujita | ||
1976 | 4 | 3 | 351 | A Double-blind Controlled Study on the Usefulness of Carpipramine-Chlorpromazine Combination in the Pharmacotherapy of Chronic Schizophrenic Patients | Osamu Inoue | Kozo Itoh | et al. | ||
1976 | 4 | 3 | 405 | Clinical Evaluation of Ketoprofen in Pain Clinic Field by a Double Blind Controlled Study | Osamu Aochi | Yukio Goto | et al. | ||
1976 | 4 | 3 | 419 | Double Blind Study of FX-505 (Ifenprodil) on Cerebrovascular Diseases −Phase V Study− | |||||
1976 | 4 | 3 | 459 | Clinical Investigation on the Haemostatic Effects of Estrogen-progestogen Combination (SH-850), Reference Drug (Equivalent to 2 tablets Norluten D) and Placebo in the Treatment of Functional Uterine Bleeding by Comparative Double Blind Method | Tsutomu Ishihara | Masami Saitoh | et al. | ||
1976 | 4 | 3 | 477 | Comparison of Clinical Efficacy of K-315 and Pentazocine in Postoperative Wound Pain Using Double Blind Techinique | Hiroshi Akimoto | Akiharu Sasaki | et al. | ||
1976 | 4 | 3 | 507 | A Double-Blind Controlled Study on the Clinical Efficacy of Topical Clobetasol 17-Propionate | |||||
1977 | 5 | 1 | 7 | Phase V Study of Anti-inflammatory Agent, 2-Phenyl-5-benzothiazoleacetic Acid (K-308)−A double blind controlled trial on acute upper respiratory infections− | Takashi Furuie | Junzaburo Kabe | et al. | ||
1977 | 5 | 1 | 23 | Phase V Study of 2-Phenyl-5-benzothiazoleacetic Acid (k-308)−A double-blind controlled trial of 2-phenyl-5-benzothiazoleacetic acid in the treatment of pain and subjective signs followed on tonsillectomy− | Kazumitsu Ishikawa | Hatsuo Ino | Osamu Kitami | ||
1977 | 5 | 1 | 31 | Clinical Evaluation of Protizinic Acid for Neck, Shoulder and Arm Symdrome with Double Blind Method | Toyoji Ueo | Hideo Watanabe | et al. | ||
1977 | 5 | 1 | 55 | Clinical Evaluation of Protizinic Acid on Diseases in Orthopedics −Double Blind Controlled Study on Neck, Shoulder and Arm Pain Compared with Mepirizole− | Masahiro Ishihara | Tsunemaru Yoshida | et al. | ||
1977 | 5 | 1 | 83 | Double Blind Clinical Trial of Protizinic Acid on Episiotomy Compared with Mepirizole and Placebo | Hirosuke Takekida | Motoo Washio | et al. | ||
1977 | 5 | 1 | 103 | A Double-Blind Study on Clinical Efficacy of Urea Ointment | |||||
1977 | 5 | 1 | 127 | Therapeutic Effect of Isoxsuprine Hydrochloride (Duvadilan) on the Glaucomatous Visual Field Changes−A Double Blind Controlled Study− | Harumi Nose | Hiroshi Koike | et al. | ||
1977 | 5 | 2 | 189 | A Multi-institutional Double Blind Control Study to Compare the Effectiveness of TM-906 and Metoclopramide in Controlling Functional Gastrointestinal Symptoms | Sho Isogai | Toshie Onuki | et al. | ||
1977 | 5 | 2 | 205 | A Double-blind Cross Over Study of Panabolide on the Male Infertility | Sadao Kamidono | Keizo Shida | et al. | ||
1977 | 5 | 2 | 213 | Double-blind Study on the Clinical Effect of Beclomethasone Dipropionate Inhaler and Its Placebo in the Treatment of Steroid-independent Bronchial Asthma | |||||
1977 | 5 | 2 | 231 | Double-blind trial to Compare Bitolerol and Trimetoquinol in Bronchial Asthma | Yoshihiko Horiuchi | Shoichi Nakagawa | et al. | ||
1977 | 5 | 2 | 255 | Evaluation of Mepitiostane for Advanced Breast Cancer−A double-blind controlled study− | |||||
1977 | 5 | 2 | 305 | Clinical Evaluation of Indenolol in Angina Pectoris by Double Blind Crossover Study with Alprenolol | Satoshi Ohta | Michio Ogasawara | et al. | ||
1977 | 5 | 2 | 341 | Double-Blind Comparison of Clinical Effects of ID-540,(Fludiazepam) Diazepam and Placebo on Psychoneuroric Patients and a Tentative Draft of Dependency Questionnaire | Masaya Jimbo | Tetsuya Hirose | et al. | ||
1977 | 5 | 2 | 369 | Comparison of Clinical Efects of Clotiazepam, Diazepam and Placebo on Neurosis Using Double Blind Technique | Kozo Itoh | Koichi Itoh | et al. | ||
1977 | 5 | 2 | 435 | A Case of Lithium Intoxication with Neurological Sequelae | Masanao Kurihara | Masanobu Uchigata | et al. | ||
1977 | 5 | 3 | 467 | Clinico-pharmacological Study on Obsessional Neurosis and Phobia with Bromazepam, Haloperidol, Imipramine and Placebo | Toshiyuki Naito | Mitsuyuki Ikeda | Yukio Suzuki | Yukio Takahashi | Hiroshi Utena |
1977 | 5 | 3 | 493 | A Double Blind Controlled Study on the Clinical Effects of Pranoprofen in Low Back Pain and Cervical Pain −Comparison with flufenamate・Aluminium− | Yutaka Miyanaga | ||||
1977 | 5 | 3 | 535 | Clinical Evaluation on Anti-Swelling Drug-A-4700(Reparil Tablet) in Orthopedic Field−A Comprehensive Double Blind Controlled Trial Compared with Serratiopeptidase and Placebo in 20 Orthopedic Clinics− | Yoshio Oi | Makoto Furuya | et al. | ||
1977 | 5 | 3 | 577 | A Double-Blind Controlled Study of the Clinical Efficacy of Topical Bendazac | |||||
1977 | 5 | 3 | 597 | A Double-Bliond Controlled Study on the Clinical Utility of Topical Fluocortolone | |||||
1977 | 5 | 3 | 633 | Evaluation of Antihypertensive Effect and Clinical Usefulness of Mebutamate | |||||
1977 | 5 | 3 | 659 | Clinical Evaluation on the Effect of Cyclandelate in the treatment of Cerebrovascular Diseases−Double-blind comparative placebo-controlled clinical study with cinnarizine as a basic treatment− | Masao Kase | Takashi Kutsuzawa | et al. | ||
1978 | 6 | 1 | 15 | A Double Blind Controlled Study on the Hemostatic Effect of Synthetic Estrogen and Gestagen Combination Drug, SH 850 on Functional Uterine Bleeding | Seiji Matsuda | Kiyoshi Saitoh | et al. | ||
1978 | 6 | 1 | 29 | Phase T Study of ID-4708, A Butyrophenone type Antipsychotic −A single dose study− | Seiichi Ichimaru | Yoshio Kudo | Osamu Shimada | ||
1978 | 6 | 1 | 45 | A Clinical Effect of Dilazep (AS-05) on Ischemic Heart Diseases −A Comparative Double Blind Clinical Study with Prenylamine− | Kenichi Harumi | Kizuku Kuramoto | et al. | ||
1978 | 6 | 1 | 69 | A Multi-Clinical Double-Blind Controlled Study on the Clinical Efficacy of Proglumide in Gastric Ulcers | Yoshihiro Kohli | Soro Takeda | et al. | ||
1978 | 6 | 1 | 85 | The Hypotensive Effects of Propranolol Compared with Those of Practolol over a Prolonged Period | T. Fujise | A. Sakuma | et al. | ||
1978 | 6 | 1 | 99 | The Comparative Efficacy of Maprotiline and Amitriptyline in Depression by Multi-Centre Double Blind Trial and the Characteristics of Maprotiline | Atsuyoshi Mori | Takuro Noguchi | et al. | ||
1978 | 6 | 2 | 145 | Effect of Oral Administration of Tioponin on Senile Cataracts −A Double Blind Clinical Study− | Kitetsu Imaizumi | Yutaka Tazawa | et al. | ||
1978 | 6 | 2 | 167 | Therapeutic Effects of Lysozyme and Tiopronin on Chronic Active Hepatitis−A Double Blind Clinical Trial− | Hiroshi Suzuki | Tatsuro Takino | et al. | ||
1978 | 6 | 2 | 201 | Clinical Effects of Lorazepam on Insomnia in the Field of Internal Medicine−Evaluated by Double Blind Study Using Nitrazepam and Placebo as Control Drugs− | Tatsuro Kokubu | Einosuke Ueda | et al. | ||
1978 | 6 | 2 | 223 | Comparison of Clinical Efficacy of Methixene, Trihexyphenidyl and Promethazine in Drug-Induced Parkinsonism Using Double Blind Cross-over Technique | Gohei Yagi | Teruyoshi Kobayashi | et al. | ||
1978 | 6 | 2 | 273 | Clinical Effects of Pyrihioxine in Treatment of Cerebrovascular Disorders −A Double Blind Controlled Study with Placebo− | Teruo Omae | Shoshiro Kuromaru | et al. | ||
1978 | 6 | 2 | 291 | Evaluation of the Clinical Efficay of So-called Brain Metabolism Activating Agents on Consciousness of Acute Cerebrovascular Diseases−Evaluation of Meclofenoxate Hydrochloride Injection by a Double-blind Method− | |||||
1978 | 6 | 2 | 317 | Clinical Effects of RONICOL Timespan for Peripheral Circulatory Disorders | |||||
1978 | 6 | 2 | 333 | Evaluation by the Double Blind Method of Long Term Effect of Antihyperlipidemic Agent on Hyperlipidemia | Hajime Orimo | Chikayuki Naito | et al. | ||
1978 | 6 | 3 | 379 | Double-Blind Controlled Study on the Efficacy of Topical Diflucortolone Valerate | |||||
1978 | 6 | 3 | 411 | Results of a Double-Blind Controlled Trial to Compare Lipoclin and Clofibrate | Yuichi Yamamura | Teruo Omae | et al. | ||
1978 | 6 | 3 | 441 | The Therapeutic Effect of S-8527 (Lipoclin) on Hyperlipidemia −Double Blind analysis of S-8527 with Clofibrate− | Youichi Umetada | Tsutomu Hara | et al. | ||
1978 | 6 | 3 | 463 | Clinical Evaluation of S-8527 (Lipoclin) in Hyperlipidemia by Double Blind Study with Nicomol | Noboru Yoshimine | Michihiro Kitagawa | et al. | ||
1978 | 6 | 3 | 483 | Double-blind Comparative Trial of S-8527 (Lipoclin) and Clofibrate on Hyperlipidemia | Iwao Fukui | Yochinori Akazawa | et al. | ||
1978 | 6 | 3 | 511 | Evaluation of Inhalated Lysozyme Ohloride, in Nebulizer Treatment upon Paranasal Sinusitis | Hitoshi Saito | Yahachiro Toyoda | et al. | ||
1978 | 6 | 3 | 533 | A Double Blind Study of Protizine Acid −Clinical Investigation on Trauma and Postoperative Symptoms− | Masaaki Funaki | Iwao Shiga | et al. | ||
1978 | 6 | 3 | 563 | Study on the Effects of Clofedanol, A New-Antitussive, by Double Blind Method −In Comparison with Dextromethorphan− | |||||
1979 | 7 | 1 | 11 | Clinical Evaluation of MK-950 in Angina Pectoris Using Double-Blind Cross-over Technique with Propranolol | Mototaka Murakami | Toshio Ozawa | et al. | ||
1979 | 7 | 1 | 27 | The Comparative Evaluation of Talampicillin Hydrochloride with Amoxycillin on Bacterial Pneumonia Patients by Double Blind study | Yutaka Ohsaki | Akira Saito | et al. | ||
1979 | 7 | 1 | 49 | Double-blind, Cross-over Study of the Effects of Ritalin, Sp-732 and Placebo on Narcolepsy | |||||
1979 | 7 | 1 | 83 | A Double-Blind Study on Utility of Econazole Cream in Dermatomycosis | |||||
1979 | 7 | 1 | 109 | Clinical Evaluation of Metoprolol, A Cardioselective Beta-Blocker on Angina Pectoris −Double-blind Comparison with Propranolol− | Hideo Miyashita | Yoshiro Nakamura | et al. | ||
1979 | 7 | 1 | 137 | Clinical Evaluation of the α-HCC (1 α-Hydroxycholecalciferol) on Hypocalcemia of Hemodialysis Patients −Comparison with Vitamin D2 by a double blind controlled clinical study− | Yosuke Ogura | Shozo Koshikawa | et al. | ||
1979 | 7 | 1 | 157 | The National Epidemiological Study of the Newly Admitted Patients of Drug Abuse in Mental Hospitals in japan during 1976 | Takemitsu Henmi | Eiko Kurisu | Haruko Shikimori | Toshiharu Fujita | |
1979 | 7 | 2 | 205 | A Double-blind Clinical Study on the Expectorant Effect of Seaprose-S | Motoichi Tanaka | Eiro Tsubura | et al. | ||
1979 | 7 | 2 | 233 | Phase T Study of Y-8910, A new Butyrophenone Derivative | Seiichi Ichimaru | Yukio Kawakita | Osamu Shimada | ||
1979 | 7 | 2 | 265 | Clinical Evaluation of Indomethacin Ointment in the Minor Trauma (contusion, bruise and sprain) −A Double-Blind Comparative Trial of Indomethacin Ointment− | Hideya Hanaoka | Mitsuyoshi Uzawa | et al. | ||
1979 | 7 | 2 | 285 | A Double Blind Controlled Study of Indomethacin Ointment −Clinical Investigation in the Orthopaedic Field− | Kanji Hichikawa | Masaki Tsujimoto | et al. | ||
1979 | 7 | 2 | 311 | Therapeutic Effect and Safety of FR 1949 on Biliary and Pancreatic Disease −Evaluation by Double-Blind Test− | Akima Miyoshi | Yoshimi Tamazawa | et al. | ||
1979 | 7 | 2 | 323 | Clinical Evaluation of Tolperisone (Muscalm) in Bronchial Asthma −Comparative Study with Control Drug Trimetoquinol by Double Blind Cross-Over Method− | Hitoshi Nagano | Mitsuru Iwakura | et al. | ||
1979 | 7 | 2 | 349 | Clinical Evaluation of Cinepazide in the Treatment of Cerebrovasucular Disorders −Multi-center double-blind study in comparison with placebo− | |||||
1979 | 7 | 2 | 379 | A Double-Blind Study Comparing Behyd W (a combination drug of Behyd and Mebutamate) with Behyd as the Reference Drug | |||||
1979 | 7 | 3 | 437 | Double Blind Study on Clinical Effects on Ganmalon in The Cerebro-Vascular Disorders | Sunao Sato | Tsuneo Nishimura | et al. | ||
1979 | 7 | 3 | 459 | A Double-Blind Controlled Clinical Study of FM-100 in Gastric Ulcer | Akima Miyoshi | Takashi Miwa | et al. | ||
1979 | 7 | 3 | 509 | Comparison of Anti-Manic Efficacy of Carbamazepine and Chlorpromazine by Double-Blind Controlled Study | Kazutoyo Inanaga | Saburo Otsuki | et al. | ||
1979 | 7 | 3 | 533 | Clinical Evaluation of ID-4708, a Newly Synthesized Butyrophenone Derivative, on Schizophrenia−Early Phase U Open Trial− | Kaizawa Shigeo | Sadanori Miura | et al. | ||
1979 | 7 | 3 | 565 | Clinical Pharmacological Study of Nomifensine a New Antidepressant −Viewed from drug dependence− | Masanao Kurihara | Takemitsu Henmi | et al. | ||
1979 | 7 | 3 | 587 | A Clinical Trial on Dependence Liability of a New Oral Antidiarrheal Agent, Loperamide Hydrochloride | Eiichi Sugimoto | Toru Abei | et al. | ||
1979 | 7 | 3 | 603 | Double-Blind Controlled Study on the Efficacy of Topical Halcinonide | et al. | (Clinical Research Group for Halcinonide) | |||
1979 | 7 | 3 | 633 | Follow-up Study on "Effect of Oral Administration of Tiopronin on Senile Cataracts" | Kitetsu Imaizumi | Yutaka Tazawa et al. | et al. | ||
1980 | 8 | 1 | 19 | Clinical Evaluation of GABA in the Treatment of Cerebrovascular Disorders−Multi-center double-blind study in comparison with pyrithioxine and placebo− | et al. | (Cooperation Study Group on Clinical Evaluation of GABA) | |||
1980 | 8 | 1 | 79 | A Study of the Clinical Efficacy of Triazolam on Insomnia−Double-blind Cross-over Study among the Smaller and Larger Doses of Triazolam, and Flurazepam− | Masaya Jinbo | Tetsuya Hirose | et al. | ||
1980 | 8 | 1 | 111 | Clinical Evaluation of GB94 (mianserin hydrochloride) on Antidepressant Effects Using Double-Blind Comparative Technique with Imipramine | et al. | (Hokkaido Clinical Psychopharmacological Research Group) | |||
1980 | 8 | 1 | 149 | Clinical Evaluation of U-600 on Gastric Ulcer | Tadayoshi Takemoto | Itaru Ohi | et al. | ||
1980 | 8 | 1 | 169 | A Double-Blind Study on the Optimum Dose of Atenolol in Essential Hypertension | |||||
1980 | 8 | 1 | 197 | A Randomized, Double Blind Controlled Trial of the Efficacy of Stronger Neo-Minophagen C for the Prevention of Post-transfusion Hepatitis | Kaneo Kikuchi | Akira Tateda | et al. | ||
1980 | 8 | 1 | 215 | Improving Effect of Prostagladin F2α(PGF2α) on Post-Laparotomy Intestinal Paralysis−Double-blind Study with Pantethine− | katsuhiko Sugahara | Shoetsu Tamakuma | et al. | ||
1980 | 8 | 1 | 235 | A Double-Blind Controlled Trial of Azatadine Maleate Syrup (Idulamine Syrup) in Children with Urticaria or Atopic Dermatitis | Toru Akasaka | Minoru Baba | et al. | ||
1980 | 8 | 2 | 321 | Clinical Evaluation of Tamoxifen in Advanced Breast Cancer (Primary & Recurrent)−Double Blind Study− | et al. | (Double Blind Study Group of Tamoxifen) | |||
1980 | 8 | 2 | 353 | Clinical Evaluation of HC20-511 (Ketotifen), a New Orally Anti-Anaphylactic Compound, in Bronchial Asthma T.Multi-center double-blind study in comparison with placebo | |||||
1980 | 8 | 2 | 397 | PhaseT Study of R 343 01, A New Benzamide Derivative | Yoshio Kudo | Yukio Kawakita | Seiichi Tanaka | Osamu Shimada | |
1980 | 8 | 2 | 437 | Clinical Evaluation with Indapamide on Patients with Essential Hypertension in 22 Medical Institutions −Study on Dose Response by Double-Blind Method− | Masao Ikeda | Nagao Kajiwara | et al. | ||
1980 | 8 | 2 | 457 | A Double-blind Clinical Study of Ketoprofen on Acute Upper Respiratory Infection−Comparison with Aspirin− | Shigeru Nagaoka | Asao Hamada | et al. | ||
1980 | 8 | 2 | 481 | Clinical Effects of SH 582 (Gestonorone caproate) on Prostatic Hypertrophy −in comparison with Paraprost by double-blind technique− | Kenichiro Okada | Masuji Kuse | et al. | ||
1980 | 8 | 2 | 517 | Attitude of Patients Toward Informed Consent in Clinical Trial of New Drug | Akira Kishimoto | Yuzuru Sunami | Kazuyoshi Nakazawa | Masashi Imaoka | Hidefumi Hazama |
1980 | 8 | 3 | 553 | Clinical Evaluation of YC-93(Nicardipine hydrochloride) and Pentoxifylline in the Treatment of Cerebrovascular Disorders −A double-blind controlled study− | Shunsaku Hirai | ||||
1980 | 8 | 3 | 577 | Clinical Utility of Eunal in Treatment of Cerebrovascular Disorders −Multi-center double-blind study in Comparison with Dihydroergotoxine mesylate− | et al. | (Research Group for Eunal Phase V Clinical Study) | |||
1980 | 8 | 3 | 629 | A Multi-centered Double Blind Trial of Pimozide (Orap), Haloperidol and Placebo for Abnormal Behavior in Children Using Crossover Design | |||||
1980 | 8 | 3 | 675 | Comparative Clinical Study on Effectiveness and Safety of Cinnarizine and Betahistine on Vertigo by Double-blind Trial Test | Hideo Saito | Manabu Hinoki | et al. | ||
1980 | 8 | 3 | 719 | Clinical Evaluation of Anginal in Ischemic Heart Diseases with Reference to Adequate Dose | Kyozou Ishikawa | Satoshi Ohta | et al. | ||
1980 | 8 | 3 | 747 | A Multicenter Double-blind Study on the Efficacy of Carbenoxolone Sodium for Japanese Patients with Duodenal Ulcer in Japan | Tetsuro Taneda | Makoto Ishikawa | et al. | ||
1980 | 8 | 3 | 757 | Therapeutic Effects of Fentiazac on Common Cold −A Double-blind Clinical Study− | Fumio Nagahama | Kiyoshi Konno | et al. | ||
1980 | 8 | 3 | 789 | Clinical Evaluation of Timolol in the Treatment of Patients with Ocular Hypertension and Primary Open Angle Glaucoma Who have been Controlled on Pilocaprine −Double blind study− | Ikuo Azuma | Yoshiaki Kitazawa | et al. | ||
1980 | 8 | 3 | 821 | A Clinical Study with Metoprolol on Efficacy and Usefulness in Essential Hypertension −Double-Blind Comparative Study on Metoprolol with Reserpine− | et al. | (Study Group of CF-15) | |||
1981 | 9 | 1 | 13 | PhaseT Study of TCUK (Urokinase Derived from Tissue Culture Process) | Hideo Miyashita | Masami Yamanaka | et al. | ||
1981 | 9 | 1 | 25 | Clinical Evaluation of N-(2-ethylhexyl)-3-hydroxybutyramide hydrogen succinate (M-2H) by Double-Blind Cross-Over Study on Insomnia−Double-Blind Cross-Over Study in Comparison with Bromvalerylurea− | Goro Araki | Takeshi Tomita | et al. | ||
1981 | 9 | 1 | 71 | Clinicopharmacological Studies of Hypnotics −A controlled, double-blind study of estazolam, a new hypnotic, nitrazepam and placebo− | Hiroyuki Aoki | et al. | |||
1981 | 9 | 1 | 99 | A Double-blind Clinical Trial of the Effect of Sfericase, a Proteolytic Enzyme, on Sputum and Determination of Sfericase in Serum | Eiichi Yamanaka | Keiichi Nakagawa | et al. | ||
1981 | 9 | 1 | 117 | A Double-Blind Controlled Study on the Clinical Effects of CH-800 (Fentiazac) for Low Back Pain −Comparison with Diclofenac Na− | Yoshio Oi | Ryuzo Mikami | et al. | ||
1981 | 9 | 1 | 135 | Clinical Evaluation of Fentiazac in the Treatment of Osteoarthritis of the Knee −A double-blind clinical study in comparison with Diclofenac Na− | Torakichi Aoki | Mitsuo Igarashi | et al. | ||
1981 | 9 | 1 | 159 | Clinical Evaluation of Bupranolol Hydrochloride Drop in the Treatment of Primary Open-Angle Glaucoma and Ocular Hypertension−Multi Center Double-Blind Study in Comparison with Pilocarpine Drop− | Ikuo Azuma | Masahiro Takase | et al. | ||
1981 | 9 | 1 | 225 | TEN Type Drug Eruption by α-methyldopa | Toshiyuki Funabashi | ||||
1981 | 9 | 2 | 261 | Comparison of Clinical Effect on Neurosis of Oxazolam, Diazepam and Placebo Using Double Blind Cross Over Technique | Ryo Takahashi | Yoshio Kudo | et al. | ||
1981 | 9 | 2 | 319 | Comparison of Clinical Effect on Neurosis of Mexazolam, Diazepam and Placebo Using Double Blind Technique | Shigeo Kaizawa | Sadanori Miura | et al. | ||
1981 | 9 | 2 | 355 | Effect of Melinamide on Serum Lipids −Clinical Evaluation by Double Blind Study− | et al. | (Double Blind Study Group Melinamide) | |||
1981 | 9 | 2 | 391 | Eeffects of E-0646 on Cases of Spasticty −A Double Blind Comparison Using Tolperisone Hydrochloride− | Itsuro Sobue | Yoshiaki Tazaki | Takao Nakanishi | Eiichi Ohtomo | Katsuya Itahara |
1981 | 9 | 2 | 421 | Clinical Evaluation of Urine Alkalinizing Agent CG-120 (Uralyt-U) −Mluti-Center Well-Controlled Open Study in Comparison with Sodium Bicarbonate− | Katsuki Kawabe | Ieo Akaoka | Naokata Shimizu | Yorio Satoh | et al. |
1981 | 9 | 2 | 435 | Clinical Evaluation of the Effect of Fenoprofen Calcium against Osteoarthritis of the Knee −Double-blind Comparative Trial− | Hiroshi Aritomi | Wataru Kawaji | et al. | ||
1981 | 9 | 2 | 461 | A Double-blind Controlled Study of Azatadine Maleate Tablet (Idulamine) on Urticaria and Pruritus Cutaneus | Takashi Harada | Wataru Naka | et al. | ||
1981 | 9 | 2 | 501 | Double-Blind Controlled Study on the Clinical Efficacy of Topical Prednisolone 17-Valerate 21-Acetate | et al. | (Clinical Research Group for Prednisolone 17-Valerate 21-Acetate) | |||
1981 | 9 | 3 | 577 | Phase T Study of Sultopride (New Benzamide Derivative) | Shun Yamazumi | Kurefu Okamoto | et al. | ||
1981 | 9 | 3 | 629 | Clinical Evaluation of Comelian (Dilazep) in the Treatment of Cerebrovascular Disorders −Multi-Center double-blind study in comparison with Pentoxifylline− | et al. | (Cooperation Study Group on Clinical Evaluation of Comelian) | |||
1981 | 9 | 3 | 673 | Clinical Evaluation of HOPA (HOPATE) in the Treatment of Cerebrovascular Disorders −Multi-center double-blind study in comparison with Ifenprodil tartrate and placebo− | et al. | (Cooperation Study Group on Clinical Evaluation of HOPA) | |||
1981 | 9 | 3 | 711 | A Clinical Evaluation of a New Antianxietic Drug, Alprazolam, on Psychosomatic Diseases and Neuroses | Tetsuya Nakagawa | Ken Fukamachi | et al. | ||
1981 | 9 | 3 | 733 | Clinical Evaluation of Flunitrazepam on Insomnia in Neuropsychiatric Field −A Comparative Double-Blind Cross-Over Study with Nitrazepam− | Gohei Yagi | Masato Tateyama | et al. | ||
1981 | 9 | 3 | 769 | Anti-anginal Effects of Ko 1366, a Beta-blocker −A Multiclinical Double-blind Comparison with Propranolol− | Kizuku Kuramoto | Akira Sakuma | et al. | ||
1981 | 9 | 3 | 795 | Anti-hypertensive Effects of Bunitrolol −A Multi-Clinical Double-blind Comparison with Propranolol− | Kikuo Arakawa | Masayuki Tsuchiya | et al. | ||
1982 | 10 | 1 | 19 | Clinical Effects of Oxprenolol in Essential Hypertension −Multi-center Double-blind Study in Comparison with Reserpine− | et al. | (Research Group for OXPRENOLOL) | |||
1982 | 10 | 1 | 45 | Clinical Effects of Oxprenolol in Essential Hypertension −Multi-center Double-blind Study in Comparison with Pindolol− | et al. | (Research Group for OXPRENOLOL) | |||
1982 | 10 | 1 | 73 | Clinical Effect of Guanfacine, A Centrally Acting Antihypertensive Drug Alone on Essential Hypertension −Double-Blind Inter-group Comparative Study with α-Methyldopa as Referance Drug− | Hiroshi Ashizawa | Hyoe Ishikawa | et al. | ||
1982 | 10 | 1 | 97 | A Comparative Double-Blind Study of Alprazolam, Diazepam and Placebo in Neurosis | Ryo Takahashi | Yoshibumi Nakane | et al. | ||
1982 | 10 | 1 | 117 | A Double-Blind Study on the Clinical Effects of Bromazepam in the Disease of Circulatory System | Toshitsugu Ishikawa | Toyozo Aizawa | et al. | ||
1982 | 10 | 1 | 149 | Effect of Mepitiostane on Nephrogenic Anemia −A double-blind controlled study− | Shozo Koshikawa | Yoshio Suzuki | et al. | ||
1982 | 10 | 1 | 175 | Clinical Evaluation of Cefadroxil in the Treatment of Superficial Suppurative Skin and Soft Tissue Infections −A Double-blind Study Comparing to L-Cephalexin− | Eiichiro Nonami | Hisasi Takahashi | et al. | ||
1982 | 10 | 1 | 201 | A Study of Extra-normal Validity in the Rating List for Evaluating Abnormal Behaviors in Children | Eiko Kurisu | Yorio Satoh | |||
1982 | 10 | 2 | 237 | Evaluation of Active Drug and Inactive Placebo on Cerebrovascular Diseases in Chronic Stages −An analysis of 2,441 patients with double blind controlled studies− | |||||
1982 | 10 | 2 | 247 | A Multi-Clinic Double-Blind Controlled Study on the Clinical Efficacy of Nomifensine and Imipramine in Depression | Takuro Noguchi | Reiichi Inoue | et al. | ||
1982 | 10 | 2 | 277 | Comparison of Clinical Effects of MS-4101(Flutazolam) and Diazepam on Neurosis −Multi-Center Double-Blind Controlled Study− | Masami Saito | Toshiaki Sakai | et al. | ||
1982 | 10 | 2 | 303 | Effect of Captopril (CS-522), an Angiotensin Converting Enzyme Inhibitor in Severe Hypertension −A Controlled Comparative Study with Hydralazine− | et al. | (Study Group for CS-522) | |||
1982 | 10 | 2 | 347 | A Double-Blind Controlled Clinical Study of Benoxaprofen in the Patient with Lumbago, Cervicobrachial Syndrome, or Pertiarthritis Scapulohumeralis | Torakichi Aoki | Makoto Yamamoto | et al. | ||
1982 | 10 | 2 | 377 | Effect of Mepitiostane on Aplastic Anemia −A Double-Blind Controlled Study− | et al. | (Study Group for Mepitiostane) | |||
1982 | 10 | 2 | 393 | Effects on Intraocular Pressure and Clinical Evaluation for the Usefulness of DE-016 Ophthalmic Solution (1)−Double-Blind Group Comparative Study− | Yoshiaki Kitazawa | Shigetoshi Nagataki | |||
1982 | 10 | 2 | 429 | Effects on Intraocular Pressure and Clinical Evaluation for the Usefulness of DE-016 Ophthalmic Solution (2)−Double-Blind Cross-Over Study− | Yoshiaki Kitazawa | Shigetoshi Nagataki | et al. | ||
1982 | 10 | 2 | 469 | Clinical Evaluation of Befunolol in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension under Controlled with Pilocarpine−Multi-Center Double Blind Study in Comparing Between Three Masked Dosages− | et al. | Cooperation Study Group on Clinical Evalutation of Befunolol | |||
1982 | 10 | 2 | 515 | Serum Dopamine-β-hydroxylase Levels and Efficacy of Fusaric Acid in Tardive Dyskinesia | Yoshiki Nakano | Yasuhiko Kawachi | et al. | ||
1982 | 10 | 3 | 541 | Clinical Evaluation of KW-3149 in the Treatment of Cerebrovascular Disorders−Multi-Center Double-Blind Study in Comparison with Cinnarizine− | Goro Araki | Ryuichi Kodama | et al. | ||
1982 | 10 | 3 | 575 | Clinical Evaluation of Timorol(Blocadren), on Essential Hypertension−Doublr-blind Comparison with Pindolol− | Tadanao Takeda | Nagao Kajiwara | et al. | ||
1982 | 10 | 3 | 611 | Effectiveness of Timolol (MK-950) on Arrhythmia −Double Blind Trial in Comparison with Pindolol Using Holter Monitor− | Hirofumi Osada | Kizuku Kuramoto | et al. | ||
1982 | 10 | 3 | 643 | Comparison of Clinical Effect on Neurosis of Clobazam, Diazepam and Placebo Using Double-Blind Techinique | Hiroshi Amamoto | Reiichi Inoue | et al. | ||
1982 | 10 | 3 | 679 | A Double-Blind Controlled Study of Clobazam | Hikaru Araki | Katsumi Isoda | et al. | ||
1982 | 10 | 3 | 709 | A Double-Blind Study of Viloxazine and Imipramine in Depression | Michio Okada | Takuro Noguchi | et al. | ||
1982 | 10 | 3 | 737 | Clinical Evaluation of HC 20-511(Ketotifen), a New Oral Anti-Anaphylatic Compound, in Bronchial Asthma−U.Multi-Center Double-Blind Study in Comparison with Disodium Cromoglycate− | et al. | (HC20-511 Research Group) | |||
1982 | 10 | 3 | 787 | Clinical Evaluation of the Efficacy of Cetraxate on Acute Gastric Mucosal Lesions −Endoscopic Study by Multi-Center Double-Blind Method− | Shizo Ichioka | Takeshi Miwa | et al. | ||
1983 | 11 | 1 | 13 | Phase T Study on Lysyl-Plasminogen Derived from Human Placenta (KB-623)−T.Studies on Single-and Multiple-dose Administration− | Mutsuyoshi Kazama | Tadatoshi Kinoshita | et al. | ||
1983 | 11 | 1 | 33 | Phase T Study on Lysyl-Plasminogen Derived from Human Placenta (KB-623)−U | Mutsuyoshi Kazama | Tadatoshi Kinoshita | et al. | ||
1983 | 11 | 1 | 51 | Double-Blind Randomized Control Study with Gliclazide | Shoichi Nakagawa | Kazuo Takebe | et al. | ||
1983 | 11 | 1 | 95 | Double-Blind Randomized Control Study with Gliclazide | Fumiko Matsuda | Yasuo Sugita | |||
1983 | 11 | 1 | 101 | Double-Blind Study on the Clinical Effect of Minatol-P in the Treatment of Chronic Paranasal Sinusitis | Shozo Kawamura | Yoshio Yamazaki | et al. | ||
1983 | 11 | 1 | 133 | Clinical Evaluation of Norfloxacin in the Treatment of Superficial Suppurative Skin and Soft Tissue Infections−A Double-blind Study in Comparison with L-Cephalexin− | Eiichiro Nonami | Hisashi Takahashi | et al. | ||
1983 | 11 | 1 | 155 | Comparison of Clinical Effect on Obsessive-compulsive Neurosis of Bromazepam, Diazepam, Pephenazine, Trimipramine and Placebo Using Double-Blind Cross-Over Techinique | Kozo Itoh | Masaomi Endo | et al. | ||
1983 | 11 | 1 | 201 | Comparison of Clinical Effect on Depression of Dosulepin and Amitriptyline Using Double-Blind Technique | Masanao Kurihara | Sadanori Miura | et al. | ||
1983 | 11 | 1 | 229 | Pre-Treatment Prediction of Final Outcome of Depressive Patients under Antidepressant Therapy | masanao Kurihara | ||||
1983 | 11 | 2 | 265 | Phase T Study of YM-09151-2 (New Benzamide Derivative) | Kurefu Okamoto | Akihiko Takahashi | Sadanori Miura | ||
1983 | 11 | 2 | 339 | Clinical Utility of BV 26-723 (Brovincamine) in Treatment of Cerebrovascular Disorder−Multi-center Double-blind Study in Comparison with Ifenprodil Tartrate− | et al. | (Clinical Research Group for BV 26-723) | |||
1983 | 11 | 2 | 389 | Clinical Evaluation of EG 626 (Phthalazinol) in Central Pain and Allied Dysesthesia due to Cerebrovascular Disorders−Multi-clinical Double-blind Study in Comparison with Placebo− | Eiichi Otomo | Kazuya Ando | et al. | ||
1983 | 11 | 2 | 429 | Effects of Melinamide on Hyperlipidemia and Electrocardiogram−Clinical Evaluation by Double-Blind Comparative Study− | et al. | (Research Group for Melinamide) | |||
1983 | 11 | 2 | 461 | Clinical Evaluation of Diflunisal in the Treatment of Osteoarthritis of the Knee−A Double-Blind Conparative Study− | Takuro Sugano | Makoto Yamamoto | et al. | ||
1983 | 11 | 2 | 489 | Double-Blind Controlled Study on the Clinical Efficacy of Oral Etretinate in Psoriasis | et al. | (Clinical Research Group for Oral Etretinate) | |||
1983 | 11 | 2 | 511 | Double-Blind Clinical Evaluation of Miconazole Vaginal Tablets in the Treatment of Vulvovaginal Candidiasis | Akimitsu Hagiwara | Seiji Matsuda | et al. | ||
1983 | 11 | 3 | 555 | Clinical Utility of M-101 (moxisylyte) in Treatment of Cerebrovascular Disorders−Multi-center Double-blind Study in Comparison with Ifenprodil (tartrate)− | et al. | Cooperation Study Group on Clinical Evaluation of M-101 | |||
1983 | 11 | 3 | 591 | Clinical Evaluation of Arotinolol (S-596) for Angina pectoris−A Double Blinded Comparative Study with Propranolol− | Tomohiro Kanazawa | Kazuzo Kato | et al. | ||
1983 | 11 | 3 | 623 | Anti-Arrhythmic Effects of Arotinolol on Premature Ventricular Contraction −A Multicenter Double Blind Control Study by Comparison with Propranolol− | Seiichi Toyama | Noboru yamazaki | et al. | ||
1983 | 11 | 3 | 649 | Clinical Usefulness of Probucol in Hyperlipidemia −A Three-way Parallel Double-Blind Controlled Study− | Tadao Yasugi | Haruo Nakamura | et al. | ||
1983 | 11 | 3 | 681 | Clinical Evaluation of Flutoprazepam (KB-509), Once-a-day Administration, on Psychosomatic Disorders, Neuroses and Depressive States−A Double-Blind Controlled Study Using Lorazepam as a Standard Drug− | Tetsuya Nakagawa | Ken Fukamachi | et al. | ||
1983 | 11 | 3 | 721 | Clinical Evaluation of N-acetyl-L-cysteine(TY-0048) in Patients with Difficulty in Sputum Expectration −A Double-blind Comparative Study with Mecysteine Hydrochloride Acid Tablet and Placebo Control− | Shigeru Nagaoka | Humio Nagahama | et al. | ||
1983 | 11 | 3 | 743 | Phase T Study on at pH 4 Treated Human Immunogloblin (IG-100) | Mutsuyochi Kazama | Tadatoshi Kinoshita | et al. | ||
1983 | 11 | 3 | 763 | Phase T Study of Oral Urokinase (ZP-201) −T. Single Dose Study− | Mutsuyoshi Kazama | Tadatoshi Kinoshita | et al. | ||
1983 | 11 | 3 | 781 | Phase T Study of Oral Urokinase (ZP-201) −U. Multiple Dose Study− | Mutsuyoshi Kazama | Tadatoshi Kinoshita | et al. | ||
1984 | 12 | 1 | 15 | Phase T Study of KTH-497, A New Benzodiazepine Derivative | Yoshio Kudo | Yukio Kawakita | Osamu Shimada | ||
1984 | 12 | 1 | 43 | Double-Blind Comparison of Clinical Effects of Flutoprazepam (KB-509) and Diazepam on Psychoneuroses | Kenjiro Miyamoto | Setsuo Mizushima | et al. | ||
1984 | 12 | 1 | 81 | Clinical Evalutaion of L-5HTP in Depression −Multi-center double-blind study in parallel comparison with imipramine− | et al. | (Study Group for KS-5) | |||
1984 | 12 | 1 | 137 | A Multi-center Double-Blind Trial of Tiapride and Placebo in the Treatment of Dyskinesia in Patients with and without Parkinsonism | et al. | (Study Group for Tiapride) | |||
1984 | 12 | 1 | 195 | Clinical Evaluation of γ-Oryzanol(Hi-Z) in Hyperlipidemia −A Muticenter Double-blind Trial− | Toshitsugu Oda | Hideo Miyashita | et al. | ||
1984 | 12 | 1 | 231 | Clinical Evaluation of E-0646 (Eperisone Hydrochloride) on Cervicobrachial Syndrome, Periarthritis Scapulohumeralis and Lumbago−A Double-Blind Controlled Study− | Yasuhiro Hatsuyama | Ryuichi Nihei | et al. | ||
1984 | 12 | 1 | 275 | Clinical Evaluation of Indomethacin Cataplasm (IM-P) in the Orthopaedic Field−A Double-Blind Cross-Over Study with the Inactive Placebo− | Yoshio Komatsubara | Masami Kimura | Masaki Tsujimoto | ||
1984 | 12 | 2 | 321 | Clinical Evaluation of Amantadine hydrochloride (Symmetrel) in the Treatment of Cerebrovascular Disorders with Psychiatric Symptoms−Multi-center double-blind study in comparison with placebo− | et al. | (Study Group for Symmetrel Clinical Evaluation) | |||
1984 | 12 | 2 | 369 | Clinical Utility of Bromocriptine in Parkinsonian Syndrome −Multi-Centeric Investigation in Comparison with Amantadine Hydrochloride by Double Blind Method− | Makoto Iwata | Masao Kase | et al. | ||
1984 | 12 | 2 | 403 | Therapeutic Effect of Bromocriptine in Parkinsonian Syndrome−Combined Therapy with Levodopa in Comparison Between Bromocriptine and Placebo by Double Blind Method− | Yoshikuni Mizuno | Masao Kase | et al. | ||
1984 | 12 | 2 | 445 | Clinical Evaluation of KSP-117 (sustained release preparation of amitriptyline) on Depressive Patients−A double-blind comparison with amitriptyline− | Hitoshi Itoh | Atsuyoshi Mori | et al. | ||
1984 | 12 | 2 | 475 | Clinical Evaluation of Traxanox Sodium (Y-12141), a New Oral Anti-Allergic Compound, in Bronchial Asthma −Multi-Center Double-Blind Study in comparison with DSCG and Placebo− | et al. | (Traxanox Study Group) | |||
1984 | 12 | 3 | 611 | Clinical Investigation of Antihypertensive Efficacy of Artinolol Used Alone or in Combination with Thiazide Diuretics in Essential Hypertension −Double-blind, Comparative Study with Propranolol− | Yoshiaki Inagaki | Nagao Kajiwara | et al. | ||
1984 | 12 | 3 | 647 | Evaluation of Therapeutic Effects of Formoterol, A β-receptor Stimulating Bronchodilator, on Bronchial Asthma−A Joint Double-blind Single-dose Study at 30 Institutions (Part 1)− | et al. | (Formoterol Research Group) | |||
1984 | 12 | 3 | 671 | Evaluation of Therapeutic Effects of Formoterol, A β-receptor Stimulatinf Bronchodilator, on Bronchial Asthma−A Joint Double-blind Single-dose Study at 37 Institutions (Part 2)− | et al. | (Formoterol Research Group) | |||
1984 | 12 | 3 | 697 | Evaluation of Therapeutic Effects of Formoterol, A New β-receptor Stimulating Bronchodilator, on Bronchial Asthma−A Joint Double-blind Repeated-dose Study at 37 Instisutions− | et al. | (Formoterol Research Group) | |||
1984 | 12 | 3 | 729 | A Double-Blind Controlled Clinical Study of Oxaprozin in the Patient with Lumbago, Cervicobrachial Syndrome and Periarthritis Scapulohumeralis | Mitsuo Hasue | Tetsuya Hara | Ryuichi Nihei | ||
1984 | 12 | 3 | 765 | A Double-Blind Controlled Study of Camazepam | Seiichi Ichimaru | Tsuyoshi Nishimura | et al. | ||
1984 | 12 | 3 | 775 | The New Assessment Method of Drug Dependency | et al. | ||||
1984 | 12 | 3 | 827 | Problems of the Repeated Use of Statistical Tests on Many Response Items and for Multiple Stratification | Hiroe Tsubaki | Yorio Satoh | Masanao Kurihara | Satoshi Fujimoto | |
1985 | 13 | 1 | 19 | Effectiveness of Zopiclone (27 267 R.P.) in Insomnia −Multi-center Double-blind Study in Comparison with Flurazepam− | et al. | (Hokkaido Clinical Psycho-Pharmacological Association) | |||
1985 | 13 | 1 | 53 | Clinical Evaluation of Nomifensine on Antidepressant Effects Using Double-Blind Comparative Technique with Imipramine | Yoshio Kudo | Shosuke Watanabe | et al. | ||
1985 | 13 | 1 | 105 | Clinical Evaluation of Bromperidol, a new investigational Butyrophenone Derivative, in Schizophrenia, A Double-blind Comparison of Bromperidol and haloperidol | Hidenori Anno | Yasuo Fujii | et al. | ||
1985 | 13 | 1 | 137 | Comparison of Clinical Effect on Vegetative Dystonia of OK-O-05, Oryzanol and Placebo Using Double-Blind Technique | Tomonobu Kawano | Taisaku Katsura | et al. | ||
1985 | 13 | 1 | 169 | Endoscopic Evaluation of the Clinical Efficacy of Gefarnate on Acute Gastric Mucosal Lesions−A Comparative Double-Blind Study with Cetraxate and Placebo− | Noboru Watanabe | Shisyo Ichioka | et al. | ||
1985 | 13 | 1 | 195 | Clinical Evaluation of Liposteroid in the Treatment of Rheumatoid Arthritis, A Double-Blind Comparison with Decardron | Takamasa Kageyama | Yutaka Mizushima | et al. | ||
1985 | 13 | 1 | 229 | Clinical Evaluation of MEN-OM in the Treatment of Osteoarthritis of the Knee −A Double-Blind Comparative Study− | Chihiro Kimura | Katsumi Suzuki | et al. | ||
1985 | 13 | 1 | 257 | Phase T Study of a New Synthetic Platelet Aggregation Suppressant OPC-13013 (6-[4-(1-Cyclohexyl-1H-Tetrazole-5yl)Butoxy]-3,4-Dihydro-2(1H)-Quinolinone) | Mutsuyoshi Kazama | Tadatoshi Kinoshita | et al. | ||
1985 | 13 | 2 | 295 | Clinical Usefulness of Tiapride on Psychiatric Symptoms Caused by Cerebrovascular Disorders −A Multi-center Double-Blind Study in Comparison with Inactive Placebo− | et al. | (Study Group for Tiapride) | |||
1985 | 13 | 2 | 333 | Clinical Evaluation of MK-421 (Enalapril Maleate) in the Treatment of Severe Hypertension −A Comparative Study with Captopril− | et al. | (MK-421 Study Group) | |||
1985 | 13 | 2 | 381 | Clinical Evaluation of Medroxyprogesterone Acetate in Advanced Breast Cancer−A Double-Blind Controlled Trial with Mepitiostane− | et al. | (Japanese Group for MPA Treatment of Breast Cancer) | |||
1985 | 13 | 2 | 419 | Clinical Evaluation of an Anorexiant Mazindol in the Trearment of Obesity−Multi-Center Open Trial in Phase U− | Masakazu Abe | Akira Kumagai | et al. | ||
1985 | 13 | 2 | 461 | Clinical Evaluation of Mazindol, an Anorexiant, on Obesity −Multi-Center Double-Blind Study in Comparison with Placebo− | Akira Kumagai | Yuichiro Goto | et al. | ||
1985 | 13 | 2 | 517 | A Study of the Problem of Dependency of Mazindol −A Clinical Open Study− | et al. | (Mazindol Dependency Study Group) | |||
1985 | 13 | 2 | 549 | Phase T Study of Haloperidol Decanoate | Yukio Kawakita | Seiichi Ichimaru | et al. | ||
1985 | 13 | 3 | 613 | Clinical Evaluation of MK-421 (Enalapril Maleate), an Angiotensin-Converting Enzyme Inhibitor, Used Alone as Treatment of Essential Hypertension−Results of Double-Blind Group Comparison Study with Captopril as Control Drug− | et al. | (Results of Double-Blind Group Comparison Study with Captopril as Control Drug− | |||
1985 | 13 | 3 | 659 | Clinical Utility of Urokinase in the Treatment of Acute Stage of Cerebral Thrombosis−Multi-center Double-Blind Study in Comparison with Placebo− | et al. | (UK-BR Study Group) | |||
1985 | 13 | 3 | 711 | Clinical Efficacy of Urokinase in the Treatment of Cerebral Thrombosis −Multi-center Double-Blind Study in Comparison with Placebo− | Goro Araki | Eiichi Itoh | et al. | ||
1985 | 13 | 3 | 753 | A Multicenter Double-Blind Trial of Tiapride and Placebo in the Treatment of Tardive Dyskinesia | Gohei Yagi | Kunitoshi Kamishima | et al. | ||
1985 | 13 | 3 | 791 | Clinical Evaluation of Eptazocnine on Postoperative Pain −A Double-Blind Study in Comparison with Pentazocine− | et al. | (Study Group for Eptazocine) | |||
1985 | 13 | 3 | 813 | Phase T Study of Bromperidol | Kurefu Okamoto | Akihiko Takahashi | et al. | ||
1986 | 14 | 1 | 13 | Clinical Evaluation of OPC-13013, a New Platelet Aggregation Inhibitor, on Chronic Arterial Occlusive Diseases−Dose Finding Study by Double-Blind Method− | Tatsuzo Tanabe | Keishu Yasuda | et al. | ||
1986 | 14 | 1 | 43 | Clinical Investigation of Tizanidine (DS 103-282) on Cerebral and Spinal Paralyses −Multicentric Double-Blind Study− | Itsuro Sobue | Yasuo Toyokura | et al. | ||
1986 | 14 | 1 | 77 | Effectiveness of Zopiclone (27 267 R.P.) in Insomnia −Multi-center Double-Blind Study in Comparison with Flurazepam−(The second report) | et al. | (Hokkaido Clinical Psycho-Pharmacological Association) | |||
1986 | 14 | 1 | 109 | Clinical Evaluation of Lormetazepam (WY-4082) on Insomnia in Neuropsychiatric Field−A Multiclinical Double-Blind Comparison with Flurazepam− | Kunitoshi Kamishima | Hiroshi Hada | et al. | ||
1986 | 14 | 1 | 133 | Clinical Evaluation of BL 191 RD (Pentoxifylline Retarded Formulation), Pentoxifylline and Dilazep hydrochloride in the Treatmetnt of Cerebrovascular Disorders−A Double-Blind Controlled Study− | Hideo Tohgi | Kyuya Kogure | et al. | ||
1986 | 14 | 1 | 175 | Clinical Evaluation of Ceruletide in Schizophrenia −Multi-institutional double-blind placebo controlled study− | et al. | (Study Group for CLN) | |||
1986 | 14 | 2 | 231 | Phase T Study of Quinupramine (LM-208) A New Iminodibenzyl Derivative | Yoshio Kudo | Seiichi Ichimaru | Osamu Shimada | ||
1986 | 14 | 2 | 249 | Clinical Evaluation of Afloqualone on Cervicobrachial Syndrome and Lumbago −A Double-blind Controlled Trial− | Yasuhiro Hatsuyama | Takahide Kurokawa | et al. | ||
1986 | 14 | 2 | 279 | Clinical Evaluation of LS-121 in the Treatment of Cerebrovascular Disorders −Multi-center double-blind study in comparison with Nicardipine− | Takashi Kutsuzawa | Goro Araki | et al. | ||
1986 | 14 | 2 | 343 | Clinical Evaluation of KC-404 in the Treatment of Cerebrovascular Disorders −Multi-Center Double-blind Study in Comparison with Nicardipine Hydrochloride− | Tsuneo Hasegawa | Eiichi Ohtomo | et al. | ||
1986 | 14 | 2 | 373 | Clinical Evaluation of KC-404, a New Anti-asthmatic Agent, in the Treatment of Bronchial Asthma−Multi-center Double-blind Study in Comparison with Tranilast− | et al. | (KC-404 Study Group) | |||
1986 | 14 | 2 | 409 | Clinical Evaluation of Sultopride Schizophrenic Patients In A Double-Blind Comparison With Haloperidol | Mitsukuni Murasaki | Kunitoshi Kamijima | et al. | ||
1986 | 14 | 2 | 437 | Ciclosporin Treatment for Behcet's Disease −Double-Masked Group Comparative Study− | Akira Nakajima | Akira Urayama | et al. | ||
1986 | 14 | 3 | 487 | Phase T Study of Y-516 (A New Iminodibenzyl Compound) | Mitsukuni Murasaki | Hirofumi Wakatabe | et al. | ||
1986 | 14 | 3 | 525 | Clinical Efficacy of HWA 285 in the Treatment of Cerebrovascular Disorders −Multi-center double-blind study in comparison with calcium hopantenate− | Goro Araki | Eiichi Itho | et al. | ||
1986 | 14 | 3 | 575 | Clinical Evaluation of TA-079 (Nicergoline) in the Treatment of Cerebrovascular Disorders−Multi-center double-blind study in comparison with Ca-hopantenate− | Shunsaku Hirai | Kazuo Hasegawa | et al. | ||
1986 | 14 | 3 | 603 | Comparison of Therapeutic Efficacy on Neurosis between CM6912 (ethyl loflazepate) and Diazepam in a Double-blind Trial | Atsuyoshi Mori | Takuro Noguchi | et al. | ||
1986 | 14 | 3 | 643 | Clinical Evaluation of Ethyl Loflazepate (CM6912), Once-a-day Administration, on Psychosomatic Diseases and Neuroses −A Double-Blind Controlled Study Using Lorazepam− | Tetsuya nakagawa | Ken Fukamachi | et al. | ||
1986 | 14 | 3 | 683 | A Multicenter Clinical Evaluation of Y-8894 in Depression | Hitoshi Itoh | Atsuyoshi Mori | et al. | ||
1986 | 14 | 4 | 723 | Clinical Evaluation of EB-382 in the Treatment of Osteoarthritis of the Knee −A Double-Blind Comparative Study− | Takamasa Kageyama | Sachiko Sugawara | et al. | ||
1986 | 14 | 4 | 757 | Clinical Evaluation of Misoprostol (SC-29333) in the Treatment of Gastric Ulcer − A Multicenter Double-Blind Comparative Study with Cetraxate Hydrochloride− | Takashi Nakamura | Makoto Ishikawa | et al. | ||
1986 | 14 | 4 | 793 | Clinical Evaluation of Misoprostol (SC-29333) in the Treatment of Duodenal Ulcer − A Multicenter Double-Blind Comparative Study with Cimetidine− | Takashi Nakamura | Makoto Ishikawa | et al. | ||
1986 | 14 | 4 | 827 | Effects of Org DD-100 (Nandrolone decanoate) on Renal Anemia −A Multi-center Double-Blind Study− | Shozo Koshikawa | Toshiaki Suzuki | et al. | ||
1986 | 14 | 4 | 859 | The Clinical Efficacy of Cepharanthin 60mg/day in Cutaneous Amyloidosis −Double-Blind Controlled Study in Comparison with Cepharanthin 6mg/day− | Fumio Kaneko | Masaru Ohhashi | et al. | ||
1986 | 14 | 4 | 879 | Double-Blind Controlled Trial of Coenzyme A Injection in the Treatment of Fatty Liver | et al. | (Study Group for Fatty Liver) | |||
1986 | 14 | 4 | 893 | The Evaluation Method of Clinical Effects of Drug for Fatty Liver −Judgement of histological findings of the liver and variations of blood biochemical values from different labo-centers− | et al. | (Study Group for Fatty Liver) | |||
1987 | 15 | 1 | 15 | Comparison of Therapeutic Effect on Mania of Sultopride Hydrochloride with Haloperidol using Double-Blind Technique | Seiichi Ichimaru | Yukio Kawakita | et al. | ||
1987 | 15 | 1 | 37 | A Phase V Study of KD-136 (Haloperidol Decanoate: A Lond-Acting Neuroleptic) in the Treatment of Schizophrenia −The Detailed Analysis of Multi-Clinical Double-Blind Comparative Study of Haloperidol Decanoate with Oral Haloperidol Preparation− | et al. | (Study Group for KD-136) | |||
1987 | 15 | 1 | 73 | Clinical Effect of Nipradiol (K-351) in Combined Therapy with Thiazide Diuretic on Essential Hypertension −A Multi-central Double-blind Comparison with Propranolol − | Yoshihiro Kaneko | Kiyoshi Kuramoto | et al. | ||
1987 | 15 | 1 | 107 | Clinical Evaluation of LS-121 Injection in the Treatment of Cerebral Infarction and Cerebral Hemorrhage in Acute and Subacute Stages −Multi-center double-blind study with placebo as the control drug− | Kenji Nakajima | Goro Araki | et al. | ||
1987 | 15 | 1 | 143 | Clinical Utility of OPC-13013 in Treatment of Cerebrovascular Disorders−Multi-center double-blind study− | Shunsaku Hirai | Goro Araki | et al. | ||
1987 | 15 | 1 | 181 | Clinical Evaluation of Rilmazafone (450191-S), a New Hypnotic, in the Treatment on Insomnia in Neuropsychiatric Field−Multi-center, Double-blind, Cross-over Trial for the Comparison with Trizolam− | Toshihiko Kinoshita | Hidetoshi Miyamoto | et al. | ||
1987 | 15 | 2 | 233 | Comparison of Therapeutic Effect on Excitement State of Schizophrenia and Atypical Psychosis of Sultopride Hydrochloride with Haloperidol using Double-Blind Technique | Seiichi Ichimaru | Yukio Kawakita | et al. | ||
1987 | 15 | 2 | 253 | Clinical Efficacy of Bunitrolol Retard (Ko 1366 PL) in the Treatment of Essential Hypertension−Multi-center double-blind study in comparison with bunitrolol (Betrilol) | Yoshiaki Masuyama | Ichiro Nishio | et al. | ||
1987 | 15 | 2 | 283 | Clinical Investigation of Effects and Safety of Bunitrolol Slow-Releasing Agent (Ko1366PL) on Essential Hypertension −A Multi-Institutional Double-Blind Comparison by Fixed-Flexible Method− | Keishi Abe | Yukio Miura | et al. | ||
1987 | 15 | 2 | 307 | Clinical Evaluation of TM-906 (Trimebutine Maleate) in the Treatment of Irritable Bowel Syndrome −Multi-center double-blind study in comparison with Mepenzolate bromide− | Akima Miyoshi | Kiyoshi Kawakami | et al. | ||
1987 | 15 | 2 | 335 | Phase T Study of a New Antianxiety Drug, Buspirone | Jun Ishigooka | Akihiko Takahashi | et al. | ||
1987 | 15 | 2 | 371 | Clinical Evaluation of RU 39780 (Binedaline Hydrochloride) on Depression and Depressive States −The Double-Blind Group Comparative Study with the Control of Imipramine− | Hitoshi Itoh | Atsuyoshi Mori | et al. | ||
1987 | 15 | 2 | 381 | Influence of Ca-Hopantenate on Laboratory Values−Particularly in mentally retarded children− | Koichiro Shirahashi | Masashi Takesada | et al. | ||
1987 | 15 | 3 | 423 | Therapeutic Effects of L-DOPS in Parkinson's Disease −Double-blind, comparative study against placebo as control in patients with the long-term levodopa therapy− | Takao Nakanishi | Mitsuo Yoshida | et al. | ||
1987 | 15 | 3 | 459 | A Randomaized, Double Blind Controlled Study for 7 days on the Efficacy of Human Lymphoblastoid Interferon (HLBI) for Chronic Hepatitis B virus Infections | Takashi Matsushima | Shiro Iino | et al. | ||
1987 | 15 | 3 | 487 | Clinical Evaluation of AST-120 in the Treatment of Chronic Renal Failure −Multi-center, double-blind study in comparison with placebo− | Shozo Koshikawa | Yoshiji Yamane | et al. | ||
1987 | 15 | 3 | 527 | Clinical Evaluation of AST-120 on Suppression of Progression of Chronic Renal Failure −Multi-center, double-blind study in comparison with placebo− | Shozo Koshikawa | Yoshiji Yamane | et al. | ||
1987 | 15 | 3 | 565 | Clinical Evaluation of Temazepam on Insomnia in Neuropsychiatric Field (Except for Schizophrenic Insomnia) − Comparative Double-Blind Study with Nitrazepam− | Sadanori Miura | Mitsuaki Inami | et al. | ||
1987 | 15 | 3 | 577 | Phase T Study of Norfloxacin Ophthalmic Solution | Machiko Abe | ||||
1988 | 16 | 1 | 25 | Therapeutic Effect of Ea-0671 on Acute Gastritis and Acute Exacerbation in Chronic Gastritis −Multicenter Double-Blind Controlled Study Compared with Cetraxate, Mainly Using Endoscopic Evaluation− | Shinroku Ashizawa | Kazuhiko Iwakoshi | et al. | ||
1988 | 16 | 1 | 49 | Study on the Efficacy of Mianserin Hydrochloride −A double-blind comparative trial between a single night-time and divided daily dose regimen− | |||||
1988 | 16 | 1 | 81 | Clinical Evaluation of FUT-175, a Regional Anti-coagulant for Hemodialysis Patients with Hemorrhagic Complications −Multi-center comparative study with Heparin− | Tadao Akizawa | Yoshihei Hirasawa | et al. | ||
1988 | 16 | 1 | 115 | Comparison of Anti-Manic Efficacy of Carbamazepine and Lithium Carbonate by Double-Blind Controlled Study | Itaru Yamashita | Ryo Takahashi | et al. | ||
1988 | 16 | 1 | 149 | Phase T Study of OPC-4392 | Jun Ishigooka | Akihiko Takahashi | et al. | ||
1988 | 16 | 2 | 211 | Clinical Evaluation of CS-514 (Pravastatin) on Hyperlipidemia −Double-blind study with clinofibrate− | |||||
1988 | 16 | 2 | 251 | Clinical Evaluation of Long-term Oral Administration of OPC-8212 in the Treatment of Chronic Heart Failure −A Multicenter Placebo-controlled Double-blind Trial− | Shigetake Sasayama | Michitoshi Inoue | et al. | ||
1988 | 16 | 2 | 291 | Clinical Evaluation of Y-8864 in the Treatment of Cerebrovascular Disorders −Multi-center double-blind study in comparison with Calcium hopantenate− | Hiroshi Sekimoto | Eiichi Itoh | et al. | ||
1988 | 16 | 2 | 327 | Comparison of the Therapeutic Effect of Carbamazepine and Placebo in Schizophrenia and Atypical Psychosis by Double-Blind Controlled Study | Itaru Yamashita | Ryo Takahashi | et al. | ||
1988 | 16 | 2 | 375 | A Double-Blind Controlled Study of CM 6912 (Ethyl loflazepate) on Neurosis Using Placebo | Atsuyoshi Mori | Kenshiro Ohara | et al. | ||
1988 | 16 | 3 | 425 | Clinical Utility of HYG-FAS in Treatment of Cerebrovascular Disorders −Multi-Center Double-Blind Study in Comparison with Hydergine Tablet 2mg− | Eiichi Ohtomo | et al.(Clinical Research Study Group for HYG-FAS) | |||
1988 | 16 | 3 | 487 | Futher Analysis of the Phase V Comparative Study of KD-136 (Haloperidol Decanoate: A Long-Acting Injectable Neuroleptic) and Oral Haloperidol in the Treatment of Chronic Schizophrenia | Masanao Kurihara | et al.(Study Group for KD-136) | |||
1988 | 16 | 3 | 499 | Clinical Assessment of Gestrinone (R 2323) in Patients with Endometriosis −Multi-center double-blind study in comparison with Danazol− | et al.(Study Group for R 2323) | ||||
1988 | 16 | 3 | 547 | Phase T Study of KRN5702 (recombinant human erythropoietin) | Munehito Kumagae | Sachiko Itoh | et al. | ||
1988 | 16 | 4 | 581 | A Double-blind study of EHDP on Heterotopic Ossification after Spinal Cord Injury Using Placebo | Kiyoshi Kaneda | Kunio Takaoka | et al. | ||
1988 | 16 | 4 | 617 | Usefulness and Determination of Optimal Dose of Misoprostol in the Treatment of Gastritis in a Double-Blind Study | Takashi Nakamura | Makoto Ishikawa | et al. | ||
1988 | 16 | 4 | 643 | Dose Finding Trial of Cibenzoline in Patients with Venticular Premature Contraction using Double-blind Technique in a Multi-center Cooperation | Hiroyuki Iinuma | Takahisa Tanabe | et al. | ||
1988 | 16 | 4 | 661 | Clinical Evaluation of Lormetazepam in the Treatment of Sleep Disturbances (First Report) −Double-blind Trial in Comparison with Nitrazepam− | Sadanori Miura | Itaru Yamashita | et al. | ||
1988 | 16 | 4 | 687 | Clinical Evaluation of Lormetazepam in the Treatment of Sleep Disturbances (Second Report) −Correction of Background Bias− | Jungo Sawa | ||||
1989 | 17 | 1 | 11 | Clinical Efficacy and Safety of Cibenzoline in Patients with Ventricular Premature Contraction −A Double-blind Group Comparative Trial in Comparison with Disopyramide in a Multi-center Cooperation− | Hiroyuki Iinuma | Saichi Hosoda | et al. | ||
1989 | 17 | 1 | 35 | Clinical Efficacy and Safety of Cibenzoline in Patients with Supraventricular Premature Contraction −A Double-blind Group Comparative Trial in Comparison with Disopyramide in a Multicenter Cooperation− | Hiroyuki Iinuma | Saichi Hosoda | et al. | ||
1989 | 17 | 1 | 57 | Clinical Effects of Bepridil (Org 5730) on Premature Ventricular Contraction −A Multicenter Group Comparative Double-blind Study − | Hirokazu Hayakawa | Hirofumi Osada | et al. | ||
1989 | 17 | 1 | 77 | Clinical Evaluation of E-0659 on Atopic Dermatitis −Multicenter Double-blind Study in Comparison with Ketotifen− | |||||
1989 | 17 | 1 | 117 | Dose-Response and Duration of Betaxolol Ophthalmic Solution on Primary Open Angle Glaucoma and Ocular Hypertension −Double-Masked Cross-Over Study− | Ikuro Azuma | Makoto Araie | |||
1989 | 17 | 2 | 177 | A Double-blind Comparison of a New Iminodibenzyl Compound Y-516 with Clocapramine in the Pharmacotherapy of Schizophrenia | Ryo Takahashi | Gohei Yagi | et al. | ||
1989 | 17 | 2 | 197 | A Multicenter Double-Blind Comparative Study of 4-Week Duration on Effect of Bepridil (Org 5730) in Ventricular Premature Contraction | Hiroshi Kasanuki | Hirokazu Hayakawa | et al. | ||
1989 | 17 | 2 | 219 | Clinical Evaluation of Flecainide Acetate in the Treatment of Ventricular and Atrial Premature Contractions −Multicenter Double-Blind Study Using Disopyramide− | Yasuro Nakata | Hiroyuki Iinuma | et al. | ||
1989 | 17 | 2 | 243 | Clinical Evaluation of Betaxolol Hydrochloride in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension −Multi-Center Double-Masked Study in Comparison with Timolol− | et al. | ||||
1989 | 17 | 2 | 275 | Clinical Effect of Ketotifen Ophthalmic Solution on Allergic Conjunctivitis and Vernal Conjunctivitis −Multi-center Double-blind Study in Comparison with Disodium Cromoglycate Ophthalmic Soluaion − | Akira Nakajima | Fumio Kogure | et al. | ||
1989 | 17 | 2 | 299 | Clinical Evaluation of TD 2-01 in Maintenance Fluid Therapy −Multi-center Double-blind Study in Comparison with 10% EL-3− | Teiryo Maeda | Goro Oya | et al. | ||
1989 | 17 | 3,4 | 349 | A Double-Blind Comparison of a New Benzamide Compound YM-09151 with Haloperidol in the Treatment of Schizophrenia | Hajime Kazamatsuri | Shigeru Kaneno | et al. | ||
1989 | 17 | 3,4 | 379 | Clinical Evaluation of Quinupramine (LM-208) on Depression and Depressive State in a Multi-center Cooperation | Seiichi Ichimaru | Yukio Kawakita | et al. | ||
1989 | 17 | 3,4 | 403 | Clinical Evaluation of Quinupramine (LM-208) on Depression and Depressive States −DB study with Imipramine hydrochloride− | Seiichi Ichimaru | Yukio Kawakita | et al. | ||
1989 | 17 | 3,4 | 413 | A Multicenter Double-Blind Comparative Study on Effect of Bepridil (Org 5730) in Supraventricular Premature Contraction | Takahisa Tanabe | Hirokazu Hayakawa | et al. | ||
1989 | 17 | 3,4 | 429 | Clinical Evaluation of Bepridil (Org 5730) on Angina pectoris −Multicenter Double-blind Study in Comparison with Nifedipine− | Saichi Hosoda | Hirokazu Hayakawa | et al. | ||
1989 | 17 | 3,4 | 451 | A Double-blind, Dose-finding Study of Recombinant Tissue-type Plasminogen Activator, SM-9527 for the Intravenous Thrombolysis in Acute Myocardial Infarction | Kiyoshi Machii | Nagao Kajiwara | et al. | ||
1989 | 17 | 3,4 | 485 | Clinical Usefulness of Intravenous Application of SM-9527 (duteplase; t-PA) in Acute Myocardial Infarction −A multicentered, double-blind comparative study with intravenous administration of urokinase− | Kiyoshi Machii | Nagao Kajiwara | et al. | ||
1989 | 17 | 3,4 | 517 | A Fetal Case of Acute Lithium Intoxication with Cardiomyopathy | Hajime Kanamura | Masanao Kurihara | et al. | ||
1990 | 18 | 1 | 19 | Clinical Efficacy of Bopindolol, a New β-blocker in Angina Pectoris −Multicenter Double-Blind Comparative Study− | Tomohiro Kanazawa | Norimitsu Takahashi | et al. | ||
1990 | 18 | 1 | 39 | Clinical Efficacy of Intravenous Administration of SM-9527 (t-PA) in Cerebrak Thrombosis −Multi-center double-blind study in comparison with urokinase− | Akiro Terashi | Hideo Tohgi | et al. | ||
1990 | 18 | 1 | 71 | Clinical Evaluation of Low Molecular Weight Heparin: LHG-500 −Phase T Study: Single Dosage Test− | Kayoko Wakasugi | Chieko Tahara | et al. | ||
1990 | 18 | 1 | 95 | Clinical Evaluation of Low Molecular Weight Heparin: LHG-500 −Phase T Study: Multiple Dosage Test− | Kayoko Wakasugi | Chieko Tahara | et al. | ||
1990 | 18 | 1 | 121 | Clinical Evaluation of NFG Ophthalmic Solution in the Treatment of Viral Conjunctivitis −Multi-center, double-blind study in comparison with placebo− | Shusaku Kitano | Yukio Uchida | et al. | ||
1990 | 18 | 1 | 145 | Clinical Evaluation of Quinupramine on Depression and Depressive State | Masanao Kurihara | Hitoshi Itoh | et al. | ||
1990 | 18 | 2 | 251 | Clinical Effectiveness of KB-831(trazodone hydrochloride), a New Antidepressant,on Depression−A clinical phase U study by double-blind method− | Masanao Kurihara | Ryo Takahashi | et al. | ||
1990 | 18 | 2 | 279 | Clinical Effects of Trazodone (KB-831) on Depression−A double-blind comparative study using amitriptyline as a standard drug− | Masanao Kurihara | Ryo Takahashi | |||
1990 | 18 | 2 | 315 | Effects of Modified Release Bromocriptine on Parkinson's Disease and Parkinsonism, A Double-blind Study | Tohru Mannen | Makoto Iwata | et al. | ||
1990 | 18 | 2 | 341 | Double-Blind Study Evaluating the Efficacy of Parlodel Modified Release Capsule (PLO-MR) in the Suppression of Puerperal Lactation | Toshihiro Aono | Rihachi Iizuka | et al. | ||
1990 | 18 | 2 | 357 | Double-Blind Study Evaluating the Efficacy of Parlodel Modified Release Capsule (PLO-MR) in the Treatment of Prolactin-Related Disorders | Toshihiro Aono | Rihachi Iizuka | et al. | ||
1990 | 18 | 3 | 433 | Efficacy of a new anxiolytic, buspirone on neurosis−A comparative double-blind study with diazepam and placebo− | Mituskuni Murasaki | Shunkichi Endo | et al. | ||
1990 | 18 | 3 | 455 | Meclofenoxate Hydrochloride (Lucidril) in Tardive Dyskinesia−A Double-Blind Placebo-Controlled Sthdy− | Kunitoshi Kamishima | Sadanori Miura | |||
1991 | 19 | 1 | 15 | A Double-blind Comparative Study on the Efficacy and and Safety of Fluphenazine Decanoate (SQ 10, 733) and Oral Haloperidol in the Treatment of Schizophrenic Patients | Teruo Ohkuma | et al.(Study Group of FD) | |||
1991 | 19 | 1 | 47 | Clinical Evaluation of Pravastatin (CS-514) in Once Daily Therapy on Hyperlipidemia−Double-blind Comparative Study between Once Daily and Twice Daily Therapy− | Akira Yamamoto | Yuichiro Goto | et al.(Study Group of CS-514-10) | ||
1991 | 19 | 1 | 93 | Phase T Study of Risperidone, a New Antipsychotic Drug of Benzisoxazol Derivative | Hirobumi Wakatabe | Mitsukuni Murasaki | et al. | ||
1991 | 19 | 2 | 213 | A Multicenter Double-blind Comparison Study of Amlodipine and Nicardipine-retard in Patients with Esseneial Hypertension | Mikio Arita | Osamu Iimura | et al. | ||
1991 | 19 | 2 | 243 | Clinical Evaluation of SIT-150, a Glucose Contained Bicarbonate Dialysate−Multi-center Comparative Study with a Glucose Free Dialysate− | Yoshihei Hirasawa | Kazuo Ota | Shozo Koshikawa | Yousuke Ogura | et al. |
1991 | 19 | 2 | 267 | Experimental Design and Analysis for Determination of Improvement Rating by Video Imaging−A Double-Blind Placebo-Controlled Study for Meclofenoxate Hydrochloride (Lucidril) in Tardive Dyskinesia− | Michiko Tsubaki | Gohei Yagi | et al. | ||
1991 | 19 | 3 | 315 | Clinical Utility of CT-848 (Oxiracetam) in the Treatment of Cerebral Infarction−A multi-center, double-blind study in comparison with Idebenone− | Hideo Togi | Shunsaku Hirai | et al. | ||
1991 | 19 | 3 | 355 | Clinical Efficacy of Amlodipine Besylate on Angina Pectoris−Multicenter Double-Blind Comparative Dose-Finding Study− | Hiroshi Kishida | Yotaro Oyama | et al. | ||
1991 | 19 | 3 | 379 | Clinical Evaluation of Amlodipine Besylate on Angina Pectoris−Multicenter Double-blind Comparative Study with Nifedipine Retard− | Yotaro Oyama | Seiichi Toyama | et al. | ||
1991 | 19 | 3 | 405 | Evaluation of the Quality of Life in Patients with Cerebrovascular Diseases | Hideyuki Sawada | Masakuni Kameyama | |||
1991 | 19 | 4 | 439 | Clinical Efficacy and Safety of Intravenous Cibenzoline in the Treatment of Patients with Ventricular Premature Contractions | Hiroyuki Iinuma | Hiroshi Inoue | et al. | ||
1991 | 19 | 4 | 461 | Clinical Evaluation of Intravenous Cibenzoline in Treatment of Paroxysmal Supraventricular Techycardia−A Multicenter Double-blind Study in Comparison with Placebo− | Hiroyuki Iinuma | Takahisa Tanabe | et al. | ||
1991 | 19 | 4 | 477 | Clinical Evaluation of Intravenous Cibenzoline in Treatment of Paroxysmal Atrial Fibrillation or Paroxysmal Atrial Flutter−A Multicenter Double-blind Study in Comparison with Placebo− | Hiroyuki Iinuma | Tsuneaki Sugimoto | et al. | ||
1991 | 19 | 4 | 491 | Effects of Single Bolus Injection of Low Molecular Weight Heparin (LHG-500) as an Anticoagulant for Hemodialysys−Double-Blind Cross-over Study in Comparison with Continuous Administration of Conventional Heparin− | Tadao Akizawa | Nobuhide Mimura | et al. | ||
1991 | 19 | 4 | 541 | Effects of LHG-500 (Low Molecular Weight Heparin) as an Anticoagulant for Hemodialysis Patients with Bleeding Risks−Multi-instirutional Control Study with Low Dose or Regional Heparinization− | Tadao Akizawa | Nobuhide Mimura | et al. | ||
1992 | 20 | 1 | 11 | Clinical Evaluation of Temocapril Hydrochloride (CS-622), an Angiotensin-Converting Enzyme Inhibitor, Used Alone for Treatment of Essential Hypertension−Results of Double-Blind Enalapril Maleate-Controlled Study− | Keishi Abe | Osamu Iimura | et al. | ||
1992 | 20 | 1 | 45 | Clinical Evaluation of Ea-0167 (Menatetrenone) in the Treatment of Osteoporosis−Phase V Double-blind Multicenter Comparative Study with Alfacalcidol− | Masataka Shiraki | et al. | |||
1992 | 20 | 1 | 101 | Clinical Evaluation of Low Calcium Dialysate AKLK-64−Well contorolled Cross-Over Stndy of AKLK-64 and Kindaly Solution AF-2P− | Yoshihei Hirasawa | Yousuke Ogura | et al. | ||
1992 | 20 | 1 | 131 | Clinical Evaluation of Pirmenol in Treatment of Ventricular Premature Contractions −A Multicenter Double-Blind Dose Finding Study− | Hiroshi Kasanuki | Hiroyuki Iinuma | et al. | ||
1992 | 20 | 1 | 161 | Phase-T Study of Savoxepin, A New Tetracyclic Antipsychotic | Mitsukuni Murasaki | Hirobumi Wakatabe | et al. | ||
1992 | 20 | 2 | 225 | Clinical Evaluation of Tandospirone (SM-3997), on Psychosomatic Diseases with Gastrointestinal Complaints−A Comparative Double-Blind Controlled Study with Diazepam and Placebo− | Toshiie Sakata | Tetsuya Nakagawa | et al. | ||
1992 | 20 | 2 | 259 | Late Phase U Study of a New Anxiolytic, SM-3997 (Tandospirone) on Neurosis | Atsuyoshi Mori | Shunkichi Endo | et al. | ||
1992 | 20 | 2 | 295 | Efficacy of a New Anxiolytic, Tandospirone (SM-3997) on Neurosis−A comparative double-blind study with diazepam− | Atsuyoshi Mori | Shunkichi Endo | et al. | ||
1992 | 20 | 2 | 331 | Clinical Usefulness of Clentiazem Maleate in Patients with Essential Hypertension−A Multicenter Double-blind Trial Compared with Diltiazem Hydrochloride− | Kaoru Yoshinaga | Tadanao Takeda | Masao Ikeda | et al. | |
1992 | 20 | 2 | 359 | Clinical Utility of TA-3090 in the Treatment of Chronic Stages of Cerebrovascular Disorders−Double-blind study in comparison with Nicardipine− | Kunio Tashiro | Kyuya Kogure | et al. | ||
1992 | 20 | 3 | 447 | Clinical Study of Buspirone on Neurosis−A comparative double-blind trial with placebo− | Masahiro Asai | Koichi Ito | et al. | ||
1992 | 20 | 3 | 477 | Clinical Evaluation of Angiotensin Converting Enzyme Inhibitor, Trandolapril (RU44570) in Patients with Essential Hypertension−Multi-centerd double-blind comparative study in comparison with enalapril maleate− | Takao Saruta | Osamu Iimura | et al. | ||
1992 | 20 | 3 | 513 | Clinical Efficacy of Oral Cibenzoline in Patients with Supraventricular Premature Contraction−A Multi-center Double-blind Comparative Dose-finding Study− | Hiroyuki Iinuma | Saichi Hosoda | et al. | ||
1992 | 20 | 3 | 535 | A New PMS System for Collection and Feedback of Information with Computer Network | Yoshihito Ohmori | Ikuo Suzuki | et al. | ||
1993 | 21 | 1 | 21 | Clinical Evaluation of NFG Ophthalmic Solution in the Treatment of Viral Conjunctivitis−Multi-center, double-blind study in comparison with placebo− | Shusaku Kitano | Yukio Uchida | et al. | ||
1993 | 21 | 1 | 51 | Clinical Evaluation of NFG Ophthalmic Solution in the Treatment of Viral Conjunctivitis (Second Report) −Evaluation of Clnical Sgnificance by Additional Analysis− | Shusaku Kitano | Yukio Uchida | |||
1993 | 21 | 1 | 59 | The Clinical Evaluation of B-HT920 (Talipexole Hydrochloride) in Parkinson's Disease−A Multi-Centered Double-Blind Comparateve Study vs. Bromocriptine Mesilate− | Hisayuki Kowa | Yoshikuni Mizuno | Nobuo Yanagisawa | ||
1993 | 21 | 1 | 111 | Placebo Controlled Double Blind Study of E0704 (Gangliosides) in Diabetic Peripheral Neuropathy | Takao Nakanishi | Yukio Shigeta | et al. | ||
1993 | 21 | 2 | 161 | Therapeutic Effects of Recombinant Human Erythropoietin (SNB-5001) on Anemia Associated with Chronic Renal Failure | Kazuo Ota | Kimihiro Takayama | et al. | ||
1993 | 21 | 2 | 195 | Double-blind Trial of Intravenous and Subcutaneous Administrations of Recombinant Human Erythropoietin (SNB-5001) for Anemia in Hemodialysis Patients | Kazuo Ota | Kimihiro Takayama | et al. | ||
1993 | 21 | 2 | 221 | Efficacy of a New Antipsychotic, Risperidone, on Schizophrenia−A comparative double-blind study with haloperidol− | Itaru Yamashita | Yukiteru Machiyama | et al. | ||
1993 | 21 | 2 | 261 | Double-blind Multicenter Comparative Study with Alfacalcidol of Etidronate Disodium (EHDP) in Involutional Osteoporosis | Hajime Orimo | Kunio Takaoka | et al. | ||
1993 | 21 | 3 | 361 | Clinical Utility of E3810 for the Treatment of Duodenal Ulcer−Comparison with Famotidine by Multi-center Double-blind Study− | Jyunji Yoshino | et al. | |||
1993 | 21 | 3 | 383 | Clinical Evaluation of Passiflamin (Passiflora Extract) on Neurosis−Multi-center, double-blind study in comparison with Mexazolam− | Kazuo Hasegawa | Yoshio Kudo | et al. | ||
1993 | 21 | 3 | 441 | Phase T Trial on the Serotonin Reuptake Inhibitor SME3110 (fluvoxamine maleate) | Hirobumi Wakatabe | Eiko Shimada | et al. | ||
1993 | 21 | 3 | 491 | Study on Reliability and Validity of the Japanese Version of Yale-Brown Obsessive Compulsive Scale (JY-BOCS) | Michihiko Nakamura | Chiaki Taga | et al. | ||
1994 | 22 | 1 | 61 | Clinical Study on Long-term Drug Treatment of Mild Essential Hypertension−Multicenter double-blind trial by group comparison of carteorol and hydrochlorothiazide− | |||||
1994 | 22 | 1 | 105 | Thrombolytic Therapy of SM-9527 (Duteplase; rt-PA) in Hyperacute Embolic Stroke −The clinical efficacy and safety of thrombolytic agent in a randomaized double-blind study− | Takenori Yamaguchi | Hiroshi Abe | et al. | ||
1994 | 22 | 1 | 141 | Phase 1 Study of Remoxipride | Tetsuo Kyohno | Mitsukuni Murasaki | Sadanori Miura | ||
1994 | 22 | 2,3 | 211 | Clinical Study of SMC20-051 Nasal Spray in Pain due to Osteoporosis−Phase U Dose-finding study− | Takuo Fuita | Seizo Yoshikawa | et al. | ||
1994 | 22 | 2,3 | 233 | Clinical Evaluation of SMC20-051 Nasal Spray in the Treatment of Pain due to Osteoporosis−A Multicenter Double-blind Comparative Study with Placebo− | Takuo Fuita | Seizo Yoshikawa | et al. | ||
1995 | 23 | 1 | 13 | Clinical Evaluation of KB-2796 (lomerizine hydrochloride) on Migraine−Late Phase U Study− | Kunio Tashiro | Naoyuki Kutsuzawa | et al. | ||
1995 | 23 | 1 | 39 | Clinical Evaluation of Milnacipran Hudrochloride, a New Antidepressant for Depression snd Depressive State−Phase V Clinical Trial with Mianserin Hydrochloride as a Control Drug− | Sadanori Miura | Mitsukuni Murasaki | et al. | ||
1995 | 23 | 1 | 65 | Therapeutic Effects of SNB-5001 (Recombinant Human Erythropoietin) on Anemia Associated with Chronic Renal Failure−Double-blind Clinical Study− | Kazuo Ota | Tadao Akizawa | et al. | ||
1995 | 23 | 1 | 87 | Long-term Effects of Recombinant Human Erythropoietin (SNB-5001) on Anemia Associated with Chronic Renal Failure | Kazuo Ota | Tadao Akizawa | et al. | ||
1995 | 23 | 2 | 183 | Clinical Evaluation of Lomerizine on Migraine−Double-blind Study in Comparison with Dimetotiazine− | Yasuo Fukuuchi | Kunio Tashiro | et al. | ||
1995 | 23 | 2 | 215 | Clinical Evaluation of GRS-001(fenofibrate) on Hyperlipidemia −Double-blind Group Comparative Study between Administration in the Morning and Evening− | Yoshiya Hata | Hiroshige Itakura | Yasushi Saito | ||
1995 | 23 | 2 | 247 | Study on the Usefulness of GRS-001 in Hyperlipidemia −Double-blind Group Comparison Trial Using Clinofibrate Tablet as the Reference Drug− | Yuichiro Goto | Tsuguhiko Nakai | et al. | ||
1995 | 23 | 2 | 307 | Clincal Effects and Pharmacokinetics of GRS-001(Fenofibrate) in Hyperlipidemic Patients with Renal Dysfunction− | Nobuyoshi Hirose | Takao Saruta | Yoshiro Nakamura | ||
1995 | 23 | 2 | 333 | Therapeutic Effects of SNB-5001(recombinant human erythropoietin) in Anemia Patients on Continuous Ambulatory Peritoneal Dialysis(CADP) −Double-blind Clinical Study− | Kazuo Ota | Tadao Akizawa | et al. | ||
1995 | 23 | 2 | 357 | Reliability of the Japanese Version of Brief Psychiatry Rating Scale(BPRS) | Yasuo Fujii | Ataru Inagaki | et al. | ||
1995 | 23 | 3 | 523 | Effect of Fenofibrate(GRS-001) in Hyperlipidemic Patients with Hyperuricemia −A Randomized, Double-Blind, Placebo-Controlled Crossover Study− | Gen Yoshino | Yoshiki Nishizawa | et al. | ||
1995 | 23 | 3 | 553 | Effect of Fenofibrate(GRS-001) on Lipoproteins and Lipoprotein Lipase Activity in Patients with Hypertriglyceridemia(Type Ub, W and X) −Double-Blind, Cross-Over Placebo controlled Study− | Kyosuke Yamamoto | Masato Ageta | et al. | ||
1995 | 23 | 3 | 581 | Pharmacokinetics of GRS-001 in the Elderly | Noriaki Nakaya | ||||
1995 | 23 | 3 | 595 | Efficacy of an Antiplatelet Agent, E5510, for Recurrence of Cerebrovascular Events in Transient Ischemic Patients −A Double-blind Comparison with Ticlopidine Hydrochloride− | Shinichiro Uchiyama | Hideo Tohgi | et al. | ||
1996 | 24 | 1 | 9 | Clinical Efficacy of E5510(satigrel), an Antiplatelet Agent, for Preventing Blood Clotting in the Extracorporeal Circuit During Hemodialysis (3) −A Double-blind Comparison with Ticlopidine Hydeochloride− | Satoshi Teraoka | Shozo Koshikawa | et al. | ||
1996 | 24 | 1 | 39 | Dose Finding Study of BAY q 7821 (Ipsapirone hydrochloride) on Neurosis −A double-blind, three group comparative study− | Sadanori Miura | Itaru Yamashita | et al. | ||
1996 | 24 | 1 | 71 | The Role and Importance of a Third Party on the Management of Postmarketing Drug Surveillance | Shimizu N | Takayama N | Adachi M | Aida T | |
1997 | 24 | 2,3 | 159 | Clinical Evaluation of a New Antipsychotic, Perosirone HCI, on Schizophrenia −A comparative double-blind study with haloperidol− | Koyama T | Miura S | et al. | ||
1997 | 24 | 2,3 | 207 | Clinical Evaluation of a Serotonin-2 and Dopamine-2 Receptor Antagonist(SDA), Perospirone HCI on Schizophrenia −A comparative double-blind study with mosapramine HCl− | Nakajima T | Saito M | et al. | ||
1997 | 24 | 2,3 | 249 | Analysis of Difference in Judgement between Video Judge Scoring Using VCR Images and Determination of FGIR by the Attending Doctor | Kurihara M | ||||
1997 | 25 | 1 | 23 | Phase U Clinical Study RG83933 Transdermal Estradiol Delivery System −Dose finding study− | Fujimoto S | Sato K | et al. | ||
1997 | 25 | 1 | 43 | The Roles of Clinical Trials in Drug Safety Information −Reporting and Analyzing Adverse Events Data in Clinical Trials− | |||||
1997 | 25 | 1 | 53 | A Comparison of the Frequencies of Adverse Drug Reactions Between Phase V Clinical Trials and Postmarketing Follow-up Studies −The Case of Antihypertensive Drugs− | Shimizu N | Ishii M | et al. | ||
1998 | 26 | 1 | 35 | Clinical Outcome Prediction of the Drugs for Cerebrovascular Diseases by Tree-based Model | Mogi K | Tsubaki H | Kurihara M | ||
1998 | 26 | 1 | 61 | Recruitment of Trial Participants and Protection of Their Human Right and Interest in Clinical Trials for New Drugs | Ishii M | ||||
1998 | 26 | 2 | 145 | Early Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -8 or 12-weeks, Open Parallel Study, 1mg/day, 2mg/day- | Imai Y | Homma A | Hariguchi S | et al. | |
1998 | 26 | 2 | 165 | Early Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -8〜12-weeks Open Study in 3mg/day- | Imai Y | Homma A | Hariguchi S | et al. | |
1998 | 26 | 2 | 185 | Late Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -8-weeks Double-blind Parallel Study in Two Groups, 2mg/day, 0.1mg/day- | Homma A | Imai Y | Hariguchi S | et al. | |
1998 | 26 | 2 | 209 | Late Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -24〜48-weeks Double-blind, Placebo-Controlled Study- | Homma A | Imai Y | Hariguchi S | et al. | |
1998 | 26 | 2 | 233 | Late Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -12-weeks dose titration study, 3mg/day, 4mg/day, 5mg/day for every 4 weeks- | Imai Y | Homma A | Hariguchi S | et al. | |
1998 | 26 | 2 | 251 | Late Phase U Clinical Study of Acetylcholinesterase Inhibitor E2020 in Patients with Alzheimer-type Dementia -12-weeks Double-blind, Placebo-Controlled Study, 3mg/day, 5mg/day- | Homma A | Imai Y | Hariguchi S | et al. | |
1999 | 26 | 3 | 419 | Clinical Utility of TJ-960 in Patients with Localization Related Epilepsy -Late Phase U Study: Multicenter, Double-Blind Study in Comparison with Placebo- | Nakane Y | Yamauchi T | Onuma T | et al. | |
1999 | 27 | 1 | 83 | Roles and Significance of the Subjective Global Judgements by Investigators in Confirmatory Clinical Trials | Tsubaki H | Kurihara M | |||
1999 | 27 | 1 | 101 | Phase T Study of Quetiapine Fumarate (ICI 204,636,Zeneca) on Healthy Male Volunteer | Murasaki M | Shimada E | Yoshimoto S | et al. | |
2000 | 27 | 3 | 615 | Effect of cilostazol, an antiplatelet agent on transient ischemic attack (TIA)-A double-blind, randomized, controlled trial of cilostazol versus Aspirin- | Gotoh F | Tohgi H | Hirai S | et al. | |
2000 | 28 | 1 | 97 | Long-term safety and efficacy of acetylcholinesterase inhibitor E2020 in patients with Alzheimer-type dementia-52-week open label study- | Tohgi H | Homma A | Imai Y | et al. | |
2001 | 28 | 3 | 569 | Late Phase U study of Y-23684 on Neurosis-A placebo-controlled comparative randomized double-blind study- | Miura S | Murasaki M | Kudo Y | et al. | |
2005 | 32 | 1 | 213 | Individual consumption of Mifepristone (RU486) as an oral abortion pill | Matsumoto K | Saotome T | |||
2005 | 32 | 1 | 233 | Problems in clinical activities by medical students: Political institutionalization of non-licensed medical practices for education and training purposes | Inoue Y | ||||
2005 | 32 | 1 | 259 | Survey of the attitude of physicians, patients and clinical research coordinator on clinical trials | Fukunaga T | Ikeda H | Tsukamoto H | et al. | |
2005 | 33 | 1 | 213 | Study on development and evaluation of new over-the-counter drugs by the actual use trial (AUT) using OTC common cold medicine including ibuprofen | Shimizu N | Notani J | Nishikawa T | et al. | |
2005 | 33 | 1 | 241 | Logarithmic equation in Japanese drug pricing rules as a main determinant of the abrupt price rising of growth hormone products | Kamada I | Saio T | |||
2008 | 35 | 3 | 593 | Survey results of clinical data management education in medical institutions in Japan | Kanda N | Uno H | Aotani E | Takahashi F | |
2008 | 35 | 3 | 609 | Survey for utilization of Electronic Data Capture in clinical trials conducted by pharmaceutical companies in Japan | Matsuba H | Yamamoto K | Teramukai S | Fukushima M | |
2008 | 36 | 2 | 393 | Questionnaire survey on the institutional review boards in Fukuoka aiming at the construction of the board member education system | Sasaguri T | Shibata T | Ueguchi M | et al. | |
2008 | 36 | 2 | 421 | The activities of IRBs organized in the JACIC member facilities for phase T clinical studies | Iijima H | Momma T | Fukazawa I | et al. | |
2008 | 36 | 2 | 433 | Japan Association of Site Management Organizations (JASMO) Institutional Review Board (IRB) survey −Preliminary results and discussion− | Matsushima M | Kobayashi T | Iwakami K | et al. | |
2009 | 36 | sup26 | 173 | Current status of Japanese universities' management of conflict of interest in clinical research −Survey of conflict of interest policies and rules− | Saotome C | Yoshida K | Teranishi Y | ||
2011 | 38 | 4 | 839 | Education and training for ethics board members: Is e-learning the solution? | Tajima M | Nagamura F | |||
2011 | 39 | 1 | 5 | Protection of human subjects and compensation for research-related injuries Proposal of explanation sheet based on survey of the actual status in Japan | Watanabe H | Kageyama S | Kusuoka H | et al. | |
2011 | 39 | 2 | 395 | Current status in the regulation of research that involves human subjects in South Korea and China | Motojima M | Ichikawa I | |||
2011 | 39 | 3 | 601 | Present situations and future of the educational environment for the clinical development in Japan: A study based on a questionnaire survey | Somekawa L | Kurokawa T | |||
2012 | 40 | 1 | 179 | The central laboratory tests system in clinical trials: From the results of a questionnaire survey of physicians participating in the ASUCA Trial | Todo S | Ueshima K | Kobayashi J | et al. | |
2012 | 40 | 1 | 187 | Background factors of the participating physicians and patients enrollment:From the results of a questionnaire survey for physicians participating in the SAKURA trial | Nakamoto M | Ueshima K | Fukutomi M | et al. | |
2013 | 40 | 2 | 419 | “Cooperative IRB” issues in Japan, United States, Europe, and Asia | Kurihara C | Kageyama S | |||
2013 | 41 | 1 | 209 | The application of electromagnetic record to the Clinical Trial-related Documents for the conduct of a clinical trial | Yamaguchi M | Kondo M | Yamamoto M | et al. | |
2014 | 41 | 4 | 837 | The issue of compensation of clinical trial subjects in Japan: The rimonabant lawsuit and the Ihoken Clinical Trial Compensation Guideline 2009 |
Tsuji J | ||||
2014 | 42 | 1 | 107 | Clinical development of metreleptin for lipodystrophy | Ito T | Tada H | Tanaka S | et al. | |
2014 | 42 | 1 | 119 | Information disclosure on clinical trials by the national registries and regulatory agencies in Japan, US, and EU | Hoshi J | Fujii H | Takasaki K | et al. | |
2015 | 43 | 1 | 265 W91 |
Information usage of patients with muscular dystrophy about clinical trials and its challenge | Noguchi S | Sato H | |||
2016 | 44 | 1 | 151 | Preliminary study of neuro-immune cross-talk by gut microbiota for perioperative management in infants with congenital heart disease | Imamura O | Uyeda T | Saito Y | et al. | |
2016 | 44 | 3 | 405 | The key to success in translational research and critical path research Part 1: Capability of model animal in translational research Part 2: Mechanistic equality in animal disease models and human disease |
Fukushima M | Kimura Y | |||
2016 | 44 | 3 | 453 | Taught by a dynamism of approval history of U.S. FDA as regards the process of changing labels of new drugs | Morimoto K | Tanimura N | Haraguchi M | Ichimaru K | |
2017 | 45 | 1 | 9 | Ensure reliability of clinical trials: Considering ICH-GCP(R2) and the system of clinical trial in Japan | Kono K | ||||
2017 | 45 | 1 | 45 | Puzzling out the tragedy of Rennes: The death of a healthy volunteer in the first-in-human trial in France | Kurihara C | Saio T | Nudeshima J | ||
2017 | 45 | 2 | 455 | Regulations for clinical trial and human subject protection in the United States | Kurihara C | ||||
2017 | 45 | 2 | 481 | On the ICMJE clinical trial data sharing statement: Its background and summary of its issue | Kurihara C | Saio T | |||
2017 | 45 | 3 | 609 | Threat of terrorism by using chemical and biological warfare agents: Bioluminescence assay as a military biodefense | Imamura O | Mwange VM | |||
2017 | 45 | 3 | 649 | International comparative study on clinical trial and human subject protection regulations−International norms, Japan, United States, South Korea, Taiwan, and South Africa− | Kurihara C | ||||
2018 | 45 | 4 | 685 | Comparison of approval timing and changing process of labels of three new innovative antibody medicines originated in Japan with those of FDA and EMA | Morimoto K | Kobayashi T | Shibata H | Ishii-Watabe A | |
2018 | 45 | 4 | 701 | Application of public healthcare insurance system for the treatment of research-related injury | Nabeoka Y | Kurihara C | Mimura M | Koike R | Watanabe H |
2018 | 46 | 1 | 83 | Possibility for improvement in Namibian health and drug development: eHealth security for fingerprint authentication | Imamura O | Matsi F | Kaulihowa T | Mgori NK | Kuda Y |
2018 | 46 | 2 | 303 | Comparing GCP requirements for serious adverse event reporting in the US, EU, and Japan−The impact of GCP renovation on the Japanese Clinical Trials Act 2017− | Ohtsu H | Shinano H | Matsuoka K | Yonemoto N | Sase K |
2018 | 46 | 2 | 335 | Compensation for clinical trial-related injury in sponsor-initiated or investigator-initiated trials of drugs, medical devices, and regenerative medical products: Commonalities and differences in the applicability of JPILA guidelines | Kurihara C | Koike R | Okada K | et al. | |
2019 | 46 | 3・4 | 435 | Research infrastructure for individual participant data sharing in clinical trials | Kono K | ||||
2019 | 47 | 1 | 87 | Current FDA or EMA approval status of biopharmaceuticals developed in Japan: focus on hormones, cytokines, and enzymes | Morimoto K | Kobayashi T | Shibata H | Ishii-Watabe A | |
2019 | 47 | 1 | 99 | Availability of the outcomes of clinical studies conducted under the Clinical Trials Act for pharmaceutical application | Araki Y | Sugita H | Sasaki T | ||
2019 | 47 | 1 | 115 | Considering the future of clinical research at the turning point of implementation of the new legislation in Japan−Impact of the Clinical Trials Act on Pharmaceutical Industries; Based on the results from the internal survey in JPMA− | Ohshima H | Aoyagi M | Tajima M | et al. | |
2019 | 47 | 1 | 127 | A proposal to improve the implementation of the Clinical Trials Act, based on the comparison of the three research regulations in Japan−Report 1: the quality and safety assurance of investigational medicinal products− | Kurihara C | Suzuki C | Koike R | et al. | |
2019 | 47 | sup36 | 135 | Roles of an Academic Research Organization (ARO) in the Investigator-Initiated Development of a Medical Device: A representative case of the TITANBRIDGE® | Nishimura T | Sanuki T | Isono T | et al. | |
2020 | 47 | 3 | 399 | Awareness survey on Patient and Public Involvement (PPI) for Japanese drug development professional | Tsuda T | Okura M | Fukuta Y | Imamura K | |
2020 | 48 | 2 | 355 | Utilization of Information and Communication Technology in IRBs as a countermeasure against the COVID-19 outbreak and future challenges | Tsutsumi N | Kurihara C | Matsuyama K | et al. | |
2020 | 48 | 3 | 535 | Considering the future of clinical research at the turning point of implementation of the new legislation in Japan−Consideration of flexible use of clinical evidence and current Japanese regulations; Lessons learned from the COVID-19 pandemic− | Ohshima H | Aoyagi M | Tajima M | et al. | |
2021 | 48 | sup37 | 147 | Dubious justifiability of involuntary hospitalization: A cross-cultural, system-dynamic analysis | Park H | Saio T | Dhai A | Kurihara C | |
2021 | 49 | 1 | 7 | The effects on sales volume share of value-added generic drugs 〜A complex analysis of pharmaceutical companies’ motivation to develop value-added generic drugs〜 |
Hamada C | ||||
2021 | 49 | 1 | 29 | A study on a strategic model to implement remote auditing | Tsutsumi N | Matsuyama K | Nagashima H | Imamura K | |
2022 | 49 | 3 | 443 | Analysis of epidemiological data including an interaction in symptom occurrence−From the “Nagoya City Cervical Cancer Vaccination Survey” | Shitara S | Morikawa T | |||
2022 | 50 | 1 | 5 | The current state of the French Law on Research involving Human Being: As a result of the adjustment of doctrine and practice under the EU regulation | Nudeshima J | ||||
2022 | 50 | 1 | 21 | Challenges and proposals for improvement of the implementation of the Clinical Trial Act, based on the comparison of the three research regulations in Japan−Report 2: focusing on data-driven research and privacy protection− | Kurihara C | Mimura M | Oi H | et al. | |
2022 | 50 | 2 | 259 | Considering the future of clinical research at the turning point of implementation of the new legislation in Japan −Consideration of regulatory approval system in Japan and ‘Emergency Approval System’ enforced by the amendment of the Pharmaceutical and Medical Device Act in 2022 due to the COVID-19 pandemic− |
Ohshima H | Aoyagi M | Tajima M | et al. | |
2023 | 50 | 4 | 551 | Respect for willingness of patients to participate in clinical trials | Otsuka I | Murayama H |